Projects
Brain stimulation in the age of "light": Controlling and steering cortical cellular electrophysiology for future smart neuroprosthetics employing optogenetics University of Antwerp
Low-frequency electromagnetic stimulation: exploring the (sub) cellular mechanisms in ischemic stroke Hasselt University
A spatio-temporal simulation model (a cellular automaton) of sealing that will be used in the 3rd phase to explore the future evolution of the sealing process for a number of policy scenarios. KU Leuven
Machine learning based drug repurposing to spark corneal endothelial regeneration: from cellular to molecular characterization. University of Antwerp
Repurposing of cationic amphiphilic drugs as adjuvants to enhance the cellular delivery of small interfering RNA Ghent University
The therapeutic potential of small interfering RNA (siRNA) has since long been recognized. However, its clinical translation is limited by various extra-and intracellular drug delivery barriers. The delivery of siRNA is typically facilitated by its encapsulation in lipid-or polymer nanoparticles (nanomedicines, NMs), which is essential to improve in vivo biodistribution and enhance delivery across cellular membranes. Unfortunately, upon ...
Flexible Multi Electrode Array for electrical cellular interfacing KU Leuven
Silicon is a suitable material for electrically interfacing with biological cells and tissues. However due to silicon’s high modulus and hardness relative to biological tissues, limits appear in an ability to recapitulate cellular systems in vitro. The focus here is the physical design and development of a multi electrode array that features global mechanical properties similar to in vivo tissue. Additional features may be explored such as ...
Dissecting cellular interactions underlying auto-inflammation in Familial Mediterranean Fever. University of Antwerp
Nanocellulose-based functional cellular matrices KU Leuven
Non-invasive assessment of functional, cellular and molecular mechanisms linking inflammation and cardiac remodeling after acute myocardial injury. KU Leuven
Ischemic heart disease is a leading cause of death. The metabolic, functional, cellular and structural changes after acute myocardial injury, also termed cardiac remodeling, determine residual cardiac function, development of heart failure, and survival. Acute/chronic inflammation and reperfusion not only contribute to infarct healing but paradoxically also cause aggravation of the injury. Type, extent and timing of post injury events will ...