Projects
Carbon nanomaterial enhanced optical fibres for biomedical imaging and sensing (CHARMING). University of Antwerp
TOWARDS UNDERSTANDING THE FUNDAMENTAL ASPECTS OF SECRETION MECHANISMS IN E. COLI (Cytoplasmome/secretome divide in E. coli and in vitro reconstitution of the Type 3 Secretion in EPEC) KU Leuven
To function properly, proteins need to reach their final sub-cellular destinations and acquire their final folded state. Therefore, protein targeting and transport are essential cellular processes in all kingdoms of life. Understanding how proteins become transported and folded into a functional state reveals the fundamental aspects of cellular protein biology, like cell wall biogenesis, cell division, molecule-export/uptake/degradation ...
Pharmacology of cardiovascular aging. University of Antwerp
Development of the VersaTile technique and a microdroplet assay for the ultrahigh-throughput engineering of lysins as antibacterial agents KU Leuven
The discovery and development of antibiotics have shaped modern medicine. However, our health care system is increasingly threatened by antimicrobial resistance. Despite warnings since the very beginning, overuse and misuse of antibiotics have led to the emergence and spread of antimicrobial resistance against every known antibiotic. Moreover, many pharmaceutical companies have abandoned the search and development of new antibiotics due to ...
Aeroacoustic design and analysis of advanced light-weight liner configurations for sound attenuation in ducted flows KU Leuven
In vitro system for exploring cellular force transmission during angiogenesis. KU Leuven
Organ function is dependent on the formation of a functional blood circulatory network. Angiogenesis is the process of forming new blood capillaries from pre-existing ones, where endothelial cells (ECs) residing on capillary walls invade the surrounding extracellular matrix (ECM) and form angiogenic sprouts. Cell invasion is strongly dependent on the ability of cells to generate traction forces, rendering traction generation fundamental to ...
Bio-template silica titania diatoms for gas phase photocatalysis. University of Antwerp
Influence of distinct process-induced (micro)structures on the in vitro starch digestibility of common beans: A kinetic approach KU Leuven
Transitioning towards food systems favourable for both human health and environmental sustainability has been recently identified as an immediate challenge. In this context, a significant increase in consumption of plant-based foods (e.g. cereals, fruits, legumes, nuts, vegetables) is being strongly promoted to improve health and environmental benefits. Consequently, the development of safe and nutritious food products from ...
Microfluidics for the synthetic biology of modular endolysins Ghent University
Endolysins are enzymes that degrade the bacterial cell wall, resulting in a quick cell death. They are
recognized as a novel class of antibiotics with high potential. A unique feature that differentiates
them from all know antibiotic classes is their modular nature, comprising two to four modules with
a dedicated function. Swapping of these modules yields antibiotics with desired and improved
...