Projects
FIBEr, towards a reference center for standardized mechanical validation of soft tissue prostheses KU Leuven
Functional genomics. University of Antwerp
In search for chaperone-agonizing drugs for skeletal dysplasias attributed to dominant-negative COL2A1 mutations. University of Antwerp
Process monitoring and controlled biomanufacturing of human periosteum derived progenitor cells for cell therapy applications KU Leuven
Cell-based products are an important innovation on the pharmaceutical market. These advanced therapy medicinal products are able to regenerate defects or treat diseases, where other pharmaceuticals fail or only treat the symptoms instead of the disease. The applications of such cell-based therapies vary between treating cancer with chimeric antigen receptor T-cell therapy and regenerating cartilage or bone defects with a cell-based tissue ...
Aberrant mechanical loading in knee osteoarthritis KU Leuven
Osteoarthritis (OA) is the most common form of arthritis and one of the most prevalent chronic joint disease that especially affects the knee joint. Roughly, knee OA affects 12% of people aged 60 years or older. Although a well-documented joint disorder, the cause of OA is not fully understood, and despite medical advances, there is no effective treatment for OA. Excessive knee loading and/or changes in the normal load bearing contact can ...
Magnetically-driven biofabrication of cartilaginous assembloid implants for osteochondral regeneration KU Leuven
Prometheus: Division of skeletal tissue engineering KU Leuven
Prometheus, is an interdisciplinary, translational, research platform focusing on skeletal tissue engineering and technology transfer. Members include the Divisions of Rheumatology, Orthopaedics, Biomechanics, Experimental Medicine and Endocrinology, Prosthetic Dentistry, Bioresponses (Bioscience Engineering), the Department of Materials Engineering (KU Leuven), and the Division of Biomechanics (University of Liège). Consisting of 50+ PhD ...