Non-invasive assessment of functional, cellular and molecular mechanisms linking inflammation and cardiac remodeling after acute myocardial injury. KU Leuven
Ischemic heart disease is a leading cause of death. The metabolic, functional, cellular and structural changes after acute myocardial injury, also termed cardiac remodeling, determine residual cardiac function, development of heart failure, and survival. Acute/chronic inflammation and reperfusion not only contribute to infarct healing but paradoxically also cause aggravation of the injury. Type, extent and timing of post injury events will ...