Projects
Improving monitoring of cardiac function in critical illness: from advanced echocardiographic technology to metabolic and biochemical biomarkers predicting myocardial dysfunction. KU Leuven
Chapter 1: Validation of a deep neural network which integrates segmentation and as well as deformation imaging analysis in a large image database of echocardiograms. The objective of this chapter is to optimize deep learning techniques through study of a modified neural network, currently in development by the team of Jan D’hooge. This modified neural network will integrate local morphology of the myocardium derived from automated ...
Discovering the role of titin (TTN) in anthracycline-induced cardiac dysfunction in breast cancer. University of Antwerp
Discovering the role of titin (TTN) in anthracycline-induced cardiac dysfunction in breast cancer. University of Antwerp
Discovering the role of titin (TTN) in anthracycline-induced cardiac dysfunction in breast cancer. University of Antwerp
Genetic variants affecting cGMP signal transduction in early LV dysfunction and transition to heart failure: a prospective population study and proof-of-concept intervention stufy. KU Leuven
Despite significant advances in our understanding and treatment of heart failure, this syndrome remains a major public health problem and once established, it is a major cause of mortality and morbidity in Western and industrialized societies. In this project we want to focus on the role of the nitric oxide – cyclic guanosine monophosphate (NO-cGMP) signaling pathway, and more particular the genetic variants of different components in this ...
Use of Xenon anesthesia in patients at high risk for postoperative organ dysfunction KU Leuven
Despite being originally described to be chemically inert, noble gases including xenon, argon and helium have been repeatedly demonstrated to exhibit remarkable biological properties. The first use of xenon anaesthesia in humans was performed by Cullen and Gross in 1951. However, only the development of closed-circuit anaesthesia machines in the 1990’ies has made xenon available to a broader spectrum of patients. Unfortunately, the scarcity ...