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Barbed sutures in cardiac surgery University of Antwerp

Filip Haenen
Barbed sutures, which have mono-directional barbs on their exterior surfaces and a needle on one or both ends, were already described in the patent issued to Dr. John H. Alcamo in 1964. In 1999, Dr. Harry J. Buncke received a patent for his advancements in the technology and in 2004, the US Food and Drug Administration approved the first widely commercialized barbed suture. Since then, several companies have released their own proprietary ...

Should renin-angiotensin system inhibitors be stopped or not before non-cardiac surgery? Hasselt University

Sigrun Halvorsen, Pascal VRANCKX, Sean van Diepen
The global annual volume of major surgical procedures is estimated to exceed 300 million, representing ∼5% of the world's population, with numbers likely increasing due to an ageing population. 1 Approximately 85% of these are non-cardiac surgeries (NCSs). Perioperative mortality for patients over 45 years of age following NCS is around 2%, 2 with other complications, such as perioperative myocardial injury or infarction (PMIs), occurring much ...

Dementia development during long-term follow-up after surgical aortic valve replacement with a biological prosthesis in a geriatric population University of Antwerp

Ivo Deblier, Karl Dossche, Anthony Vanermen, Wilhelm Mistiaen
Surgical aortic valve replacement (SAVR) with a biological heart valve prosthesis (BHV) is often used as a treatment in elderly patients with symptomatic aortic valve disease. This age group is also at risk for the development of dementia in the years following SAVR. The research question is “what are the predictors for the development of dementia?”. In 1500 patients undergoing SAVR with or without an associated procedure, preoperative ...

Stiff left atrial syndrome with pulmonary veins occlusion after percutaneous radiofrequency ablation Vrije Universiteit Brussel

Rani Jana L Kronenberger, Kaoru Tanaka, Carlo de Asmundis, Mark La Meir

BACKGROUND: Stiff left atrial syndrome (SLAS) and pulmonary vein (PV) occlusion are rare yet potentially major life-long complications after radiofrequency ablation for atrial fibrillation. While mostly controlled by medical management, SLAS can progress to refractory congestive heart failure. Treatment of PV stenosis and occlusion remains a challenging problem with ongoing risk for recurrence regardless of techniques employed. Herein we ...

Improving care in the older and/or cardiac surgical patient. KU Leuven

Danny Hoogma
Aging is a complex process that is accompanied by diminishing physiological reserves resulting in a decreased tolerance for stressors, which is considered the basis for frailty. The demographic evolution of the population in the Western world, in conjunction with the increased incidence of cardiovascular disease, has resulted in a significant increase in older persons requiring cardiac surgery. In addition, the older surgical population ...

Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT) Vrije Universiteit Brussel

Bjørn Erik Neerland, Rolf Busund, Rune Haaverstad, Jorunn L Helbostad, Svein Aslak Landsverk, Ieva Martinaityte, Hilde Margrethe Norum, Johan Ræder, Geir Selbaek, Melanie R Simpson, et al.

INTRODUCTION: Postoperative delirium is common in older cardiac surgery patients and associated with negative short-term and long-term outcomes. The alpha-2-adrenergic receptor agonist dexmedetomidine shows promise as prophylaxis and treatment for delirium in intensive care units (ICU) and postoperative settings. Clonidine has similar pharmacological properties and can be administered both parenterally and orally. We aim to study whether ...

Case-control study on the interplay between immunoparalysis and delirium after cardiac surgery Vrije Universiteit Brussel

Shokoufeh CheheiliSobbi, Annemieke M Peters van Ton, Esther M Wesselink, Marjolein F Looije, Jelle Gerretsen, Wim J Morshuis, Arjen Slooter, Wilson F Abdo, Peter Pickkers, Mark van den Boogaard, et al.

BACKGROUND: Delirium occurs frequently following cardiothoracic surgery, and infectious disease is an important risk factor for delirium. Surgery and cardiopulmonary bypass induce suppression of the immune response known as immunoparalysis. We aimed to investigate whether delirious patients had more pronounced immunoparalysis following cardiothoracic surgery than patients without delirium, to explain this delirium-infection association.

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Timing van longslagaderklepvervanging in Tetralogie van Fallot KU Leuven

Bjorn Cools
Surgically corrected tetralogy of Fallot (TOF) patients with trans-annular patch frequently have an important pulmonary regurgitation (PR) resulting in chronic right ventricular volume overload, which has been proven to increase the risk for adverse outcomes. These patients require a valve replacement early versus late to avoid the development of life-threatening arrhythmias, heart failure and sudden cardiac death. There is, however, no ...

Position paper concerning the competence, performance and environment required for the practice of ablation in children and in congenital heart disease Vrije Universiteit Brussel

Philippe Maury, Jean Benoit Thambo, Alice Maltret, Nicolas Combes, Sébastien Hascoet, Nicolas Derval, Magalie Ladouceur, Philippe Acar, Pascal Amedro, Frederic Anselm, et al.

The population of patients with congenital heart disease (CHD) is continuously increasing, and a significant proportion of these patients will experience arrhythmias because of the underlying congenital heart defect itself or as a consequence of interventional or surgical treatment. Arrhythmias are a leading cause of mortality, morbidity and impaired quality of life in adults with CHD. Arrhythmias may also occur in children with or without ...

Hallucinations after Cardiac Surgery Vrije Universiteit Brussel

Thomas H Ottens, Iris E C Sommer, Marieke J Begemann, Maya J L Schutte, Maarten Jan Cramer, Willem J Suyker, Diederik van Dijk, Arjen Slooter

Background and Objective: Hallucinations after cardiac surgery can be a burden, but their prevalence and phenomenology have not been studied well. Risk factors for postoperative hallucinations, as well as their relation to delirium are unclear. We aimed to study the prevalence and phenomenology of hallucinations after cardiac surgery, and to study the association between hallucinations and delirium in this population. Materials and Methods: ...