Projects
Functional insight in the biogenesis and specificity of the family of outer membrane porins expressed by the bacterial carcinogen Helicobacter pylori Vrije Universiteit Brussel
Transplacental carcinogenic mechanisms of black carbon exposure (T-CAB) Hasselt University
Transplacent carcinogenic mechanisms of soot exposure. KU Leuven
Ambient air pollution, including black carbon (BC), entails a serious public health risk because of its carcinogenic potential. Despite the respiratory system being the predominant entry route of particulate air pollution, various studies have indisputably demonstrated associations with a wide range of non-pulmonary health effects. A plausible explanation comprises particles translocation from the lungs into the circulation from which they ...
New alternative carcinogenic prediction assay using flatworm stem cell proliferation patterns. Hasselt University
Studying cancer prevention mechanisms in regenerative animals Hasselt University
Human liver disease: Study of the hepatic stem cells and their niche, and development of novel model systems Vrije Universiteit Brussel
Identifying molecular mechanisms underlying the effects of ethanol on eukaryotic genome instability KU Leuven
Alcohol (ethanol) is toxic to all life forms and its consumption has been associated
with numerous diseases, including cancer. Epidemiological studies have identified
causal relationships between alcohol intake and the incidence of oral cavity, larynx,
pharynx, esophagus, liver, colorectum, and female breast cancer. Yet, the molecular
mechanisms underlying the carcinogenic effect of ethanol remain elusive. It is clear ...
Planarians activate their regenerative power to circumvent cancer: the meaning of stem cell potency and its micro-environment Hasselt University
Study of the NF-kB inhibitory protein A20 in the liver and liver pathologies like hepatocellular carcinoma Ghent University
The transcription factor NF-KB is of crucial importance for inflammatory signaling, adaptive and innate immunity, development, cell survival and cell proliferation. Because of its function in a broad range of cellular processes, NF-KB signaling pathways need to be tightly regulated. One of the proteins known to play a key role in the termination of NF-KB signaling is A20, a protein which is induced by NF-KB and will terminate the signaling ...