Projects
Exploration and preclinical validation of myeloid cell pathways as novel targets and biomarkers for fibrosis development in IBD Ghent University
1) Because existing anti-inflammatory IBD therapies do not reduce the risk of fibrosis, the
innovation delivered by FIBRO-TARGET twofold. First, we will be novel and preclinical
provide validated targets for small molecule and / or biological development
molecules as drug candidates against fibrosis complications in IBD patients. Second
FIBRO-TARGET wants to ...
A license to discriminate: when, how and why do diversity policies affect employment discrimination? KU Leuven
The fields of behavioral ethics and moral psychology have demonstrated the contextual malleability of moral and immoral behavior of people. One particular observation is that people balance moral and immoral behavior on a moment-to-moment base, also referred to as moral balancing. When people engage in moral behavior, their moral self-image increases, which subsequently allows them to engage in immoral behavior (moral licensing). When people ...
Cell wall digestibility of perennial ryegrass: a strategy to increase forage quality and decrease environmental impact Research Institute for Agriculture, Fisheries and Food
Is there a way to improve perennial ryegrass so that cows can convert grass protein more efficiently into milk and meat protein? Perennial ryegrass is by far the most important grass species in Europe because of its high protein and energy content. However, up to 40% of the protein is left unused by the ruminant due to a lack of available energy. The energy content of perennial ryegrass is ...
Chemical probes for imaging bacterial proteases in lung infections. University of Antwerp
New diagnostic and prognostic antibody biomarkers for multiple sclerosis and chronic autoimmune arthritis. Hasselt University
Red clover breeding Research Institute for Agriculture, Fisheries and Food
Red clover is a perennial, protein-rich forage legume that improves soil quality through nitrogen fixation. The crop has a low persistence and is sensitive to a number of diseases, such as mildew (Erysiphe trifolii), clover rust (Uromyces trifolii) and clover rot (Sclerotinia trifoliorum). The aim of the program is to create improved varieties through conventional breeding. Important ...
Endothelial immunosuppressive mystery genes in spleen for alternative immunotherapy: dissecting their features via lipid nanoparticle-based target validation KU Leuven
The immune modulatory role of spleen: Being the largest lymphoid organ, it is widely known that the spleen can react to blood-borne antigens by initiating an immune response. The spleen is organized in two functionally distinctive regions called the red and white pulp, separated by an interface called the marginal zone. The splenic red pulp serves primarily to filter blood and recycle iron. In contrast, the white pulp allows the generation of ...
Pan-cancer liquid biopsy screening for the identification of actionable RNA biomarkers Ghent University
The biggest challenges in cancer patient management are the use of more effective and less toxic treatmant modalities, better and less invasive methods to diagnose disease, to select the right drug, to monitor treatment response and to identify relapse disease early-on. Our project proposal aims to address several of these issures by the introduction of RNA based liquid biopsy guided precision oncology. We will screen easy-to-obtain plasma ...
Narrowband phosphors for imaging Ghent University
Conclusions
This dissertation features an investigation of inorganic luminescent materials, activated by transition metal or lanthanide impurities. These materials, which are in this context referred to as phosphors, form a key building block of white LEDs, a technology that has already revolutionized, and will continue to revolutionize, electric lighting in terms of functionality, design and consumption. LED technology is not limited to ...