Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genome Ghent University
The human genome is pervasively transcribed and produces thousands of yet unexplored long non-coding RNAs (lncRNAs). With this project, we aim to uncover novel lncRNAs with therapeutic or biomarker potential in cancer. This is achieved through an elaborate discovery and validation workflow, supported by novel laboratory technologies and data analysis strategies that will be implemented during the course of this project.