Understanding the role of the WNT signaling pathway in breast cancer dormancy, therapy resistance and cancer relapse. KU Leuven
Breast cancer is the most common and most deadly neoplastic disease among women worldwide. Triple-negative breast cancer is a subtype of breast cancer characterized by the lack of expression of hormone and growth factor receptors, highly aggressive clinical features, poor prognosis, and high relapse rates. The lack of hormone and growth factor receptors renders targeted therapies that are highly efficient in other breast cancer subtypes ...