Publications
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Tight control for Crohn's disease with adalimumab-based treatment is cost-effective: an economic assessment of the CALM trial KU Leuven
OBJECTIVE: To evaluate the cost-effectiveness of an inflammatory biomarker and clinical symptom directed tight control strategy (TC) compared with symptom-based clinical management (CM) in patients with Crohn's disease (CD) naïve to immunosuppressants and biologics using a UK public payer perspective. DESIGN: A regression model estimated weekly CD Activity Index (CDAI)-based transition matrices (remission: CDAI <150, moderate: CDAI ≥150 to ...
Cysts and parasites in an abattoir in northwest Ethiopia: an urgent call for actio on "One Health" Institute of Tropical Medicine
Acoustic Emission Behaviour of Prestressed Concrete Sleepers Under Quasi-static Homologation Testing Vrije Universiteit Brussel
Prestressed concrete sleepers (PCS) play a key role in providing lateral,
longitudinal and vertical stability of railway track systems. Its capacity to fulfil these
tasks is principally examined through "homologation" tests based on crack initiation
and propagation. However, the current classical technique for crack detection by use
of a graduated microscope inspects only the surface while its accuracy is limited. ...
longitudinal and vertical stability of railway track systems. Its capacity to fulfil these
tasks is principally examined through "homologation" tests based on crack initiation
and propagation. However, the current classical technique for crack detection by use
of a graduated microscope inspects only the surface while its accuracy is limited. ...
Damage Accumulation in Cyclically-Loaded Glass-Ceramic Matrix Composites Monitored by Acoustic Emission Vrije Universiteit Brussel
Barium osumilite (BMAS) ceramic matrix composites reinforced with SiC-Tyranno fibers are tested in a cyclic loading protocol. Broadband acoustic emission (AE) sensors are used for monitoring the occurrence of different possible damage mechanisms. Improved use ofAE indices is proposed by excluding low-severity signals based onwaveformparameters, rather than only threshold criteria.The application of such improvements enhances the accuracy of the ...
Parameter based AE analysis Vrije Universiteit Brussel
The present chapter discusses the parameter-based analysis of AE. This is particularly useful in case full
waveform recording is not available, or the acquisition rate is not sufficient to allow waveform streaming.
Parameter analysis is based on extraction of descriptors that contain most of the waveform information,
without however, the need to store the whole number of points, essentially contributing to data
management. ...
waveform recording is not available, or the acquisition rate is not sufficient to allow waveform streaming.
Parameter analysis is based on extraction of descriptors that contain most of the waveform information,
without however, the need to store the whole number of points, essentially contributing to data
management. ...
Deep Remission at 1 Year Prevents Progression of Early Crohn's Disease KU Leuven
BACKGROUND & AIMS: We investigated the effects of inducing deep remission in patients with early Crohn's disease (CD). METHODS: We collected follow-up data from 122 patients (mean age, 31.2 ± 11.3 y) with early, moderate to severe CD (median duration, 0.2 years; interquartile range, 0.1-0.5) who participated in the Effect of Tight Control Management on CD (CALM) study, at 31 sites, representing 50% of the original CALM patient population. ...
Effect of tight control management on Crohn's disease (CALM): a multicentre, randomised, controlled phase 3 trial KU Leuven
BACKGROUND: Biomarkers of intestinal inflammation, such as faecal calprotectin and C-reactive protein, have been recommended for monitoring patients with Crohn's disease, but whether their use in treatment decisions improves outcomes is unknown. We aimed to compare endoscopic and clinical outcomes in patients with moderate to severe Crohn's disease who were managed with a tight control algorithm, using clinical symptoms and biomarkers, versus ...
Direct numerical simulations of collision efficiency of cohesive sediments KU Leuven
© 2016 Elsevier Ltd. A clear understanding of the collision efficiency of cohesive sediment particles is critical for more accurate simulation of the flocculation processes. It is difficult, if not impossible, to carry out laboratory experiments to determine the collision efficiency for small particles. Direct Numerical Simulation (DNS) is a relatively feasible approach to describe the motion of spherical particles under gravity in calm water, ...
A systematic cost-benefit analysis of 29 road safety measures KU Leuven
Economic evaluations of road safety measures are only rarely published in the scholarly literature. We collected and (re-)analyzed evidence in order to conduct cost-benefit analyses (CBAs) for 29 road safety measures. The information on crash costs was based on data from a survey in European countries. We applied a systematic procedure including corrections for inflation and Purchasing Power Parity in order to express all the monetary ...