Projects
Carbonation, decalcification and recalcification of Calcium-Silicate-Hydrate KU Leuven
Background The hydration of cement is a process involving multiple compounds and steps. From the moment water is added to the cement mix, cement grains start dissolving to form an ionic solution. Oversaturation of ions leads to the precipitation of hydration products, in which Calcium-Silicate-Hydrate (C-S-H) is the main constituent phase, bearing most of the calcium in hydrated cement. The physical and chemical properties of C-S-H is of ...
The role of sclerostin in vascular calcification and the calcification paradox: necessary research for development of safe therapies to treat mineralization defects in bone and vessels. University of Antwerp
The role of sclerostin in vascular calcification and the calcification paradox: necassary research for development of safe therapies to treat mineralization defects in bone and vessels. University of Antwerp
The calcification paradox: investigation into the mechanisms underlying the association between metabolic bone disease and vascular calcification. University of Antwerp
Exploring the purinergic P2Y2 receptor as a novel target for effective treatment of vascular calcification. University of Antwerp
The role of the endothelial cell and its most important signaling molecule nitric oxide in the development of arterial media calcification, a lethal co-morbidity of aging related diseases. University of Antwerp
Nanoparticle-based targeted delivery of therapeutics against arterial media calcification, a major cardiovascular complication in elderly and patients with chronic kidney disease, diabetes and osteoporosis. University of Antwerp
Research network for Arterial Calcification University of Antwerp
Natural history and determinants of the burden of medial vascular calcification, using pseudoxanthoma elasticum as a model. Ghent University
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in Europe. This proposal addresses one of the hallmark changes in CVD and premature aging, namely medial vascular calcification (VCm). Considered a good target for diagnosis and prevention, a comprehensive understanding of the causes and consequences of VCm is lacking. We aim to contribute to this knowledge by studying a monogenic form of VCm, pseudoxanthoma elasticum ...