The calcification paradox: investigation into the mechanisms underlying the association between metabolic bone disease and vascular calcification. University of Antwerp
The role of sclerostin in vascular calcification and the calcification paradox: necassary research for development of safe therapies to treat mineralization defects in bone and vessels. University of Antwerp
Development of effective treatments for vascular media calcification, a major clinical issue in our ageing population. University of Antwerp
Investigating the role of autophagy in arterial calcification and arterial stiffness. University of Antwerp
Exploring the purinergic P2Y2 receptor as a novel target for effective treatment of vascular calcification. University of Antwerp
Nanoparticle-based targeted delivery of therapeutics against arterial media calcification, a major cardiovascular complication in elderly and patients with chronic kidney disease, diabetes and osteoporosis. University of Antwerp
The role of androgens in chronic kidney desease: a missing link in the calcification paradox? KU Leuven
Androgens are sex hormones which have a crucial role in the development and homeostasis of male and female reproductive organs. They also have effects on non-classical organs like bone, muscle, kidney, vasculature and brain. This project will further explore the androgen-kidney-bone-vascular axis, and investigate the correlations between chronic kidney disease (CKD) and gonadal status. CKD predisposes to bone demineralization and vascular ...