Projects
Emotion control in patients with comorbidity of epilepsy and depression Ghent University
This project investigates the hypothesis that depression in epilepsy is based on dysfunction in the network for emotion control. During emotion control tasks, (invasive) electro-encephalography will be used to measure task-related neural activity in depressed vs. non-depressed patients with epilepsy. This project further analyzes the effects of vagus nerve stimulation, a treatment that is effective for both epilepsy and depression.
A search for validity of a childhood dimensional model for personality pathology: stability and change, comorbidity with Axis I pathology and structural links wit adult models of personality Ghent University
Relying on an age-specific dimensional model of maladaptive traits, the current research starts from a developmental perspecitve on personality disorders and focuses on the development of personality pathology across time and the relation with the fenotypic structure of childhood DSM-IV disorders. Finally, the validity of the model is explored in its relation with existing models of personality and personality pathology.
The role of the endothelial cell and its most important signaling molecule nitric oxide in the development of arterial media calcification, a lethal co-morbidity of aging related diseases. University of Antwerp
The IMPACT model explaining trends in coronary heart disease morbidity and mortality and examining future policy options. Implementation in Belgium. Ghent University
The IMPACT model will be used to explain the recent decline in CHD mortality and morbidity in Belgium and Flanders. Secondly, we will make a projection of future CHD burden in order to get an overview of the interventions with the greatest potential in reducing the CHD burden. Finally, a cost-effectiveness analyses of different strategies will be performed.
Preventing avoidable hospital admissions and optimizing care transitions in nursing home residents KU Leuven
Due to population ageing and less availability of informal caregivers, an increasing number of older people spend the last years of their life in nursing homes (NH), where quality of care has been a long-lasting concern. Negative outcomes, such as falls, restraint use and pressure ulcers are common, because of the complex profile of residents, shortage of qualified professionals and poor working conditions. This leads to a high number of ...