Projects
Size matters! Assessing effect sizes in single-case experiments using randomization tests with applications for the treatment of chronic pain. KU Leuven
This dissertation concerns the use of randomization tests (RTs) for the analysis of experimental data from single-case experimental designs (SCEDs). This type of data often exhibit characteristics that violate the statistical assumptions made by parametric significance tests. For this reason the RT has been proposed as a viable technique for single-case data analysis as it does not require distributional assumptions or an assumption of random ...
Opioid-related structural stigma in chronic pain management: An interdisciplinary investigation. Ghent University
Given the dramatic increase in opioid prescription and associated health risks for patients, the Belgian healthcare system is developing and implementing guidelines to revise opioid use in clinical settings. However, although these policies have managed to reduce opioid use and related risks in the US, an unintended consequence has been that the use of opioids, even in strictly monitored clinical settings, has become highly stigmatized, ...
Analysis of scapsular muscle recruitment in patients with chronic shoulder and neck pain, by use of fine wire EMG and muscle functional MRI Ghent University
The overall goal is to evaluate the amount and timing of activation of the different shoulder girdle muscles, in a sample of patients with chronic neck pain and shoulder pain compared to healthy subjects. All muscles surrounding the scapula will be examined during several tasks using 2 methods of investigation: Electromyography (surface and fine-wire) and Muscle functional MRI.
Neuroinflammation as a mediator of central sensitization: Unravelling the role of glial cells in chronic low back pain Vrije Universiteit Brussel
IOF Proof of Concept: Development of dual acting drugs targeting biased Mu opioid agonism and neuropeptide FF antagonism for the treatment of actute and chronic pain Vrije Universiteit Brussel
Properties of sensory neurons in ADPKD, and their contribution to ADPKD related chronic pain Flanders Institute for Biotechnology
The added value of a behavioral weight reduction program to current best evidence rehabilitation in patients with chronic low back pain: A randomized clinical trial Vrije Universiteit Brussel
Weight Loss Intervention in Overweight/Obese People Suffering from Chronic Low Back Pain: an International Multi-center Randomized Controlled Trial (WEAVE) Vrije Universiteit Brussel
disability. The most severe and debilitated CLBP patients often have
comorbidities such as overweight and obesity. Despite the growing
body of scientific literature pointing towards the close interaction
between overweight/obesity and CLBP, few treatment programs for
people with ...
Stigma and chronic pain: How does stigma get under the skin? Ghent University
Chronic nonmalignant pain is a major health complaint. Although chronic pain often has a major
impact upon patients’functioning, not all patients with chronic pain suffer or are disabled to the
same extent. Several health psychological models have been developed to explain this variability.
For example, the Fear-Avoidance Model predicts that pain-related catastrophizing (i.e., the degree
to which ...