Publications
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Cadmium and zinc induction of ZnT-1 mRNA in an established carp cell line Research Institute for Agriculture, Fisheries and Food
The cDNA of a zinc transporter-1 (ZnT-1) gene was cloned from an established cell line derived from common carp (Cyprinus carpio) using rapid amplification of cDNA ends (RACE). Using real-time quantitative PCR, we showed that both zinc (Zn) and cadmium (Cd) transiently upregulate ZnT-1 mRNA to comparable levels. The loosely bound cellular Zn pool, as estimated using the Zn-specific probe FluoZin-3, was increased threefold after exposure to 250 ...
A novel soluble immune-type receptor (SITR) in teleost fish : carp SITR is involved in the nitric oxide-mediated response to a protozoan parasite. Vrije Universiteit Brussel
Background: The innate immune system relies upon a wide range of germ-line encoded receptors including a large number
of immunoglobulin superfamily (IgSF) receptors. Different Ig-like immune receptor families have been reported in
mammals, birds, amphibians and fish. Most innate immune receptors of the IgSF are type I transmembrane proteins
containing one or more extracellular Ig-like domains and their regulation of effector ...
of immunoglobulin superfamily (IgSF) receptors. Different Ig-like immune receptor families have been reported in
mammals, birds, amphibians and fish. Most innate immune receptors of the IgSF are type I transmembrane proteins
containing one or more extracellular Ig-like domains and their regulation of effector ...
Bacterial and microalgal communities in carp polyculture systems : composition, affecting factors and further perspectives Ghent University
Carp polyculture is the planet’s most widely practiced fish production system, using multiple fish species living in diverse trophic and spatial niches of a pond to maximize productivity. Increases in farm productivity can be supported by using healthy stock, more effective use of inputs (e.g., feed, probiotics, fertilizers), and improved disease management. However, there is a lack of understanding on how microbial host interactions can help to ...
The majority of autosomal recessive nanophthalmos and posterior microphthalmia can be attributed to biallelic sequence and structural variants in MFRP and PRSS56 Vrije Universiteit Brussel KU Leuven Ghent University
This study aimed to genetically and clinically characterize a unique cohort of 25 individuals from 21 unrelated families with autosomal recessive nanophthalmos (NNO) and posterior microphthalmia (MCOP) from different ethnicities. An ophthalmological assessment in all families was followed by targeted MFRP and PRSS56 testing in 20 families and whole-genome sequencing in one family. Three families underwent homozygosity mapping using SNP ...
The European Council and the CFSP after the Lisbon Treaty Vrije Universiteit Brussel
The Treaty of Lisbon has further reinforced the position of the European Council at the top of the Common Foreign and Security Policy (CFSP) decision-making hierarchy. This has encouraged the Heads of State or Government to go beyond their fundamental task of establishing the CFSP political priorities and strategic course, by attempting to take direct responsibility in CFSP crisis situations such as the Libyan revolt of 2011.This article reviews ...
Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974) KU Leuven
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT * Calcitonin gene-related peptide (CGRP) was first described as a potent vasodilator. * CGRP is also increasingly recognized as a key player in the pathophysiology of migraine, and CGRP receptor antagonists potentially offer a new approach for treating migraine. * A novel pharmacodynamic assay to measure CGRP receptor antagonist activity non-invasively in humans has been developed, which involves ...
Feeding and swimming modulate iono-and-hormonal regulation differently in goldfish, Carassius auratus and common carp, Cyprinus carpio KU Leuven University of Antwerp
Feeding and swimming can influence ion balance in fish. Therefore we investigated their impact on ionoregulation and its hormonal control in goldfish and common carp. As expected due to the osmorespiratory compromise, exhaustive swimming induced increases in gill Na(+)/K(+) ATPase (NKA) activity in both species, resulting in stable levels of plasma ions. In contrast to our expectations, this only occurred in fed fish and feeding itself increased ...
$^{1}H$-NMR study of the metabolome of a moderately hypoxia-tolerant fish, the common carp (**Cyprinus carpio**) University of Antwerp
All 20.000 different fish species vary greatly in their ability to tolerate and survive fluctuating oxygen concentrations in the water. Especially fish of the genus Carassius, e.g. the crucian carp and the goldfish, exhibit a remarkable tolerance to limited/absent oxygen concentrations. The metabolic changes of anoxia-tolerant crucian carp were recently studied and published. Contrary to crucian carp, the hypoxia-tolerant common carp cannot ...
Fasting goldfish, **Carassius auratus**, and common carp, **Cyprinus carpio**, use different metabolic strategies when swimming University of Antwerp
Fish need to balance their energy use between digestion and other activities, and different metabolic compromises can be pursued. We examined the effects of fasting (7 days) on metabolic strategies in goldfish and common carp at different swimming levels. Fasting had no significant effect on swimming performance (Ucrit) of either species. Feeding and swimming profoundly elevated total ammonia (Tamm) excretion in both species. In fed goldfish, ...