Artificial cells on-chip: Controlling the cell cycle in time and space. KU Leuven
Proper coordination of the cell cycle is crucial in early embryonic development, as well as in maintaining healthy growth and tissue homeostasis. The frog Xenopus laevis is an ideal model organism to study this process as it provides large and easily available eggs from which cell-free extracts are obtained. Experiments with frog egg extracts led to new insights into cell cycle regulation, later translated into mathematical models. Using ...