Projects
The investigation of arterial stiffness as a potential marker in cardio-oncology. University of Antwerp
Development and validation of human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) assays to predict functional and structural cardiac liabilities. University of Antwerp
Risk prediction and modeling of cancer therapy related cardiotoxicity KU Leuven
The emergence of an ever-growing number of cancer therapies had a significant impact on cancer survival rates and converted a terminal illness into a chronic disease. Unfortunately, cancer treatment success has been offset by increased morbidity and mortality due to treatment related comorbidities. Cardiovascular complications are among the most serious side effects, sometimes not becoming manifest until many years after completion of ...
INnovation in Safety Pharmacology for Integrated cardiovascular safety assessment to REduce adverse events and late stage drug attrition (INSPIRE). University of Antwerp
Assessment of Mechanical Dyssynchrony as Selection Criterion for CRT Treatment KU Leuven
Cardiac resynchronization therapy is an accepted treatment for patients with heart failure and conduction delays, where the contraction of the left ventricular chamber is re-synchronized by means of a dedicated pacemaker device with several electrodes. Current guideline criteria for selecting patients, however, result in a non-responder rate of approximately 35%. Some studies suggest that such non-responders are even at higher risk because of ...