Comparative genomics showsmigration and expansion has preceded the rise of Buruli ulcer in south-eastern Australia Institute of Tropical Medicine
Since 2012, cases of the neglected tropical disease Buruli ulcer, caused by infection withMycobacterium ulcerans,have increased 100-fold since 2000 around Melbourne, (population 4.4 million) the capital of Victoria in temperate south-eastern Australia. The reasons for this increase are unclear. Here, we have used whole genome sequence comparisons of 178M. ulceransisolates obtained primarily from human clinical specimens, spanning 70 years, to ...
Amoebae as potential environmental hosts for **Mycobacterium ulcerans** and other mycobacteria, but doubtful actors in Buruli ulcer epidemiology University of Antwerp Institute of Tropical Medicine
Recent advances in leprosy and Buruli ulcer (Mycobacterium ulcerans infection) Institute of Tropical Medicine
Occurrence of free-living amoebae in communities of low and high endemicity for Buruli ulcer in southern Benin University of Antwerp Institute of Tropical Medicine
Response to treatment in a prospective cohort of patients with large ulcerated lesions suspected to be Buruli Ulcer (Mycobacterium ulcerans disease) Institute of Tropical Medicine
Diagnostic accuracy of clinical and microbiological signs in patients with skin lesions resembling Buruli ulcer in an endemic region Institute of Tropical Medicine University of Antwerp
Background: The diagnosis of the neglected tropical skin and soft tissue disease Buruli ulcer (BU) is made on clinical and epidemiological grounds, after which treatment with BU-specific antibiotics is initiated empirically. Given the current decline in BU incidence, clinical expertise in the recognition of BU is likely to wane and laboratory confirmation of BU becomes increasingly important. We therefore aimed to determine the diagnostic ...
A comparison of DNA extraction procedures for the detection of **Mycobacterium ulcerans**, the causative agent of Buruli ulcer, in clinical and environmental specimens University of Antwerp Ghent University Institute of Tropical Medicine
Buruli ulcer in traveler from Suriname, South America, to the Netherlands Institute of Tropical Medicine
We report Buruli ulcer in a man in the Netherlands. Phenotyping of samples indicate the Buruli pathogen was acquired in Suriname and activated by trauma on return to the Netherlands. Awareness of this disease by clinicians in non-Buruli ulcer-endemic areas is critical for identification.