Publications
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The optimal timing for imaging brain tumours and other brain lesions with 18F-labelled fluoromethylcholine: a dynamic positron emission tomography study Ghent University
Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood brain barrier permeability Vrije Universiteit Brussel
Aims: The cytoplasmic calcium concentration ([Ca2+]i) is an important factor determining the permeability of endothelial cell layers but little is known on the effect of [Ca2+]i dynamics on endothelial function. Here, we applied several conditions that trigger [Ca2+]i oscillations and cell-to-cell propagating Ca2+ waves, and determined the involvement of connexin channels and consequent effects on endothelial barrier function, in model systems ...
The European Academy of Neurology brain health strategy : one brain, one life, one approach Ghent University
Hypofractionated frameless stereotactic intensity-modulated radiotherapy with whole brain radiotherapy for the treatment of 1-3 brain metastases Ghent University
Assessment of brain age in posttraumatic stress disorder : findings from the ENIGMA PTSD and brain age working groups Ghent University
Background Posttraumatic stress disorder (PTSD) is associated with markers of accelerated aging. Estimates of brain age, compared to chronological age, may clarify the effects of PTSD on the brain and may inform treatment approaches targeting the neurobiology of aging in the context of PTSD. Method Adult subjects (N = 2229; 56.2% male) aged 18-69 years (mean = 35.6, SD = 11.0) from 21 ENIGMA-PGC PTSD sites underwent T1-weighted brain structural ...
Structural brain changes in tinnitus: grey matter decrease in auditory and non-auditory brain areas University of Antwerp
Tinnitus, the phantom perception of sound, is a frequent disorder that causes significant morbidity. The pathophysiological mechanisms involved in tinnitus generation are still under exploration. Electrophysiological and functional neuroimaging studies give increasing evidence for abnormal functioning both within the central auditory system and in non-auditory brain areas. However, observed changes show great variability, hence lacking a ...