Projects
Risk factors associated with bladder cancer occurrence and recurrence, an epidemiological and clinical approach KU Leuven
In Flanders, invasive bladder cancer is the seventh most common cause of cancer for both sexes combined. Worldwide bladder cancer ranks ninth in cancer incidence. In men, it is the fifth most common malignancy. It affects merely older patients, the mean age of diagnosis is 72 years and the men/women ratio is 5.46. The relative 5 year survival, an approximation for the disease-specific survival, is 47% in men and 54% in women[i],[ii]. Both ...
Urinary exosomes as biomarkers for diagnosis and follow up of bladder cancer patients University of Antwerp
Evans blue as a diagnostic tool for non-muscle-invasive bladder cancer and interstitial cystitis : a preclinical study. KU Leuven
Towards a better stratification of intermediate- and high-risk non-muscle-invasive bladder cancer patients KU Leuven
Bladder cancer (BC) is the most common malignancy of the urinary tract and the ninth most commonly diagnosed cancer worldwide. More than 90% of BCs in Europe and in North America are transitional cell carcinomas (TCC), derived from the urothelium. Approximately 75% of patients with BC present with disease confined to the mucosa (stage Ta, carcinoma in situ [CIS]) or submucosa (stage T1). These categories are grouped as non–muscle-invasive ...
Phase II prospective trial to evaluate the impact of 18FFDG-PET-CT in stratifying patients with primary muscle invasive bladder cancer and tailoring the treatment accordingly Ghent University
Monitoring of the systemic immune response in metastasized melanoma and bladder cancer patients receiving immunotherapy Ghent University
Combining cystectomy and external beam radiotherapy for patients with muscle invasive bladder cancer: a phase II trial Ghent University
A radical cystectomy + extended pelvic lymph node dissection is the treatment of choice for patients with muscle invasive bladder cancer (MIBC). Despite this aggressive treatment the outcome is poor, as ultimately, 30% of the patients with >=pT3 tumours will develop a pelvic recurrence, with a 1- and 2-years survival of 8% and 3% respectively, and median survival of <4 months. A more aggressive therapeutic approach by combining ...
The role of thermoTRPs in the normal and the overactive bladder. KU Leuven
The lower urinary tract consists out of the bladder and the urethra and acts as a dynamic reservoir that can store urine and expel it at a socially convenient time. The overactive bladder syndrome (OAB) affects an estimated 12% of the adult Western population and has urgency to urinate as key symptom, although OAB patients also complain of urgency incontinence, an increased daytime micturition frequency and nocturia. During urodynamic ...
The role of stromal components in urothelial cancer KU Leuven
Bladder cancer (BC) is the most common malignancy of the urinary tract and the ninth most commonly diagnosed cancer worldwide. The incidence of BC varies from region to region and country to country. More than 90% of BCs in Europe and North America are transitional cell carcinomas (TCC), originating from the urothelium or inner wall of the bladder. Approximately 75% of patients with BC show disease confined to the mucosa (stage Ta, CIS) or ...