Projects
Data Visualisation and Visual Design in Biological and Agricultural Sciences: Unearthing Complex Insights KU Leuven
The project 'Diving Deep into Biological Data Complexity' seeks to address these challenges through the application of visual analytics and topological data analysis. Visual analytics offers a human-centric approach to data exploration, allowing researchers to intuitively interact with their contextualised data and draw insights that may be hidden in purely statistical analyses. In addition, topological data analysis will be used to capture ...
Training of young scientists in the Biological regulation of the chemokine network to improve treatment of ACTIVE inflammation KU Leuven
A number of pharmaceuticals targeting cytokine/chemokine storms in lungs are in development due to an urgent new unmet medical need strengthened by the COVID-19 pandemic. The recent death of > 6.5 million people shows that treating excessive inflammation is still a major problem. Our incomplete understanding of complex immune reactions and resulting doubts on correct drug target identification prohibit efficient drug development and ...
PC – Biological and geochemical controls of Phosphate saturation on organic Carbon in agricultural soils Ghent University
The mitigation of climate change calls for a better understanding and management of the carbon sequestration potential of soils. This project will explore and unravel the yet unkown relationship between long-term P fertilization, resulting soil P-saturation and the content, nature and stability of soil organic carbon (SOC). We postulate that an excess available P in soil substantially lowers SOC stocks in agricultural soils. Higher P ...
PC – Biological and geochemical controls of Phosphate saturation on organic Carbon in agricultural soils KU Leuven
The mitigation of climate change calls for a better understanding and management of the carbon sequestration potential of soils. This project will explore and unravel the yet unkown relationship between long-term P fertilization, resulting soil P-saturation and the content, nature and stability of soil organic carbon (SOC). We postulate that an excess available P in soil substantially lowers SOC stocks in agricultural soils. Higher P ...
Druglike FAPIs with maximal target residence time: chemical discovery and biological characterization. University of Antwerp
Querying and exploiting the spatial colorectal tumor ecosystem for novel biological, diagnostic and therapeutic insights KU Leuven
Inter and intra-tumor heterogeneity complicates cancer diagnostics and therapeutics. The use of machine learning on simple tissue stains could already reveal and quantify such heterogeneity, and such algorithms are deployed in diagnostics. We have identified single cell determinants of heterogeneity in colorectal cancer and have performed spatial analyses to address these in situ. To exploit this knowledge diagnostically and therapeutically, ...
Nanoscale electro-optical characterization of biological nanofibers and their behaviour in bio-hybrid electronic devices – towards next generation biobased and biodegradable electronics Hasselt University
Development and downstream processing of biological carbon capture and utilization technologies Ghent University
Chemical Imaging of Biological Systems by Mass Spectrometry Imaging-enhanced Coherent Raman Scattering Microscopy KU Leuven
The functioning of biological systems is made possible through intricate interactions between cells that make up the tissues and the interplay between diverse classes of molecules that make up the cells. Dysregulation of this ecosystem typically leads to disease. Recent advances in spatial omics approaches have enabled a detailed mapping of the molecular composition of tissues with retention of spatial information. One of the emerging ...