Metabolic fingerprinting towards diagnosis and prognosis of cow's milk allergy in children. Ghent University
Given the emerging evidence for the involvement of the gut microbiome in the onset of food allergy
and its resolution, this project will rely on our metabolomics platform and microbial analysis of CMA patients' biofluids, for identifying prognostic biomarkers. Specific bacterial groups involved in the biomarker formation, will be manipulated or administered to mice to aid in biomarker qualification.
Biomechanics Ghent University
The AOG Biomechanics is doing experimental and computational research on (1) biofluid flows in the cardiovascular system, the pulmonary airways and artificial organs, (2) structural mechanics (musculoskeletal system or stent inflation in an artery) and (3) mechanical interaction between fluids and structures (e.g. heart valve dynamics). The research unit aims to optimize diagnostic methods and therapies, all for the benefit of human health. ...
Understanding the structure-function relationship of cereal carbohydrates with regard to beer mouthfeel quality. KU Leuven
An integrated translational platform to improve the management and outcome of rare heritable connective tissue disease Ghent University
This interdisciplinary project aims to improve the outcome of heritable connective tissue disease. Using deep phenotyping techniques in combination with advanced genetic analysis, both in the clinic and in animal models, we expect to uncover molecular mechanisms which will inform better disease management strategies. In parallel, we aim to identify novel therapeutic targets using unbiased phenotypic screening in zebrafish models.
PRINT-4-POCT: Rapid prototyping of millifluidic devices for Point-of-Care testing applications. University of Antwerp
Computational biomechanics as a tool for personalised medicine Ghent University
Throughout history, medicine has been largely built on statistical grounds, treating individual patients as members of (potentially heterogeneous) groups, which may result in suboptimal treatment outcomes. Ideally, the general focus should be shifted from the general approach towards a more personalised medicine. This research projectU+2019s ambition is to take part in this revolution by using computational biomechanics as a tool for ...
Extracellular vesicles (EVs) are lipid-based membrane vesicles which are released by the cell either constitutively or in a regulated manner.
EVs carry a specific subset of proteins, RNAs, lipids and metabolites which reflect their originating cell type and their condition. The Evs found in biofluids contain a rich source of information about the cellular processes in both health and disease, and are very promising for diagnostic ...