Publications
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Buruli ulcer; diagnosis of Mycobacterium ulcerans disease; a manual for health care providers Institute of Tropical Medicine
Buruli ulcer; review of a reemerging mycobacterial disease Institute of Tropical Medicine
What role do traditional beliefs play in treatment seeking and delay for Buruli ulcer disease? Insights from a mixed methods study in Cameroon Institute of Tropical Medicine
Mycobacterium bovis BCG vaccination as prophylaxis against Mycobacterium ulcerans osteomyelitis in Buruli ulcer disease Institute of Tropical Medicine
Buruli ulcer disease in Cameroon rediscovered Institute of Tropical Medicine
Buruli ulcer (Mycobacterium ulcerans infection): a re-emerging disease Institute of Tropical Medicine
Mycobacterium ulcerans infection is an emerging disease that causes indolent, necrotizing skin lesions known as Buruli ulcer (BU). Approximately 10% of patients develop reactive osteitis or osteomyelitis beneath skin lesions or metastatic osteomyelitis from lymphohematogenous spread of M. ulcerans. The most plausible mode of transmission is by skin trauma at sites contaminated by M. ulcerans. Pathogenesis is mediated by a necrotizing, ...
What Role Do Traditional Beliefs Play in Treatment Seeking and Delay for Buruli Ulcer Disease? Insights from a Mixed Methods Study in Cameroon KU Leuven
BACKGROUND: Victims of Buruli ulcer disease (BUD) frequently report to specialized units at a late stage of the disease. This delay has been associated with local beliefs and a preference for traditional healing linked to a reportedly mystical origin of the disease. We assessed the role beliefs play in determining BUD sufferers' choice between traditional and biomedical treatments. METHODS: Anthropological fieldwork was conducted in community ...
Response to treatment in a prospective cohort of patients with large ulcerated lesions suspected to be Buruli Ulcer (Mycobacterium ulcerans disease) Institute of Tropical Medicine
BACKGROUND: The World Health Organization (WHO) advises treatment of Mycobacterium ulcerans disease, also called 'Buruli ulcer' (BU), with a combination of the antibiotics rifampicin and streptomycin (R+S), whether followed by surgery or not. In endemic areas, a clinical case definition is recommended. We evaluated the effectiveness of this strategy in a series of patients with large ulcers of > or =10 cm in longest diameter in a rural health ...