Publications
Cognitive processes and attitudes in bipolar disorder: A study into personality, dysfunctional attitudes and attention bias in patients with bipolar disorder and their relatives Hasselt University
Background: Research in cognitive processes and attitudes in bipolar disorder is scarce and has provided mixed findings, possibly due to differences in current mood state. It is unclear whether alterations in cognitive processes and attitudes are only related to the depressive mood states of bipolar patients or also represent a vulnerability marker for the development of future (depressive) episodes. This was investigated in the current study. ...
Desynchronization of diurnal rhythms in bipolar disorder and borderline personality disorder KU Leuven
It has long been proposed that diurnal rhythms are disturbed in bipolar disorder (BD). Such changes are obvious in episodes of mania or depression. However, detailed study of patients between episodes has been rare and comparison with other psychiatric disorders rarer still. Our hypothesis was that evidence for desynchronization of diurnal rhythms would be evident in BD and that we could test the specificity of any effect by studying borderline ...
Daily longitudinal self-monitoring of mood variability in bipolar disorder and borderline personality disorder KU Leuven
BACKGROUND: Traditionally, assessment of psychiatric symptoms has been relying on their retrospective report to a trained interviewer. The emergence of smartphones facilitates passive sensor-based monitoring and active real-time monitoring through time-stamped prompts; however there are few validated self-report measures designed for this purpose. METHODS: We introduce a novel, compact questionnaire, Mood Zoom (MZ), embedded in a customised ...
The prevalence and predictors of obstructive sleep apnea in major depressive disorder, bipolar disorder and schizophrenia: A systematic review and meta-analysis KU Leuven
BACKGROUND: Obstructive sleep apnea (OSA) is a health hazard since it is associated with neurocognitive dysfunction and cardio-metabolic diseases. The prevalence of OSA among people with serious mental illness (SMI) is unclear. METHOD: We searched major electronic databases from inception till 06/2015. Articles were included that reported the prevalence of OSA determined by polysomnography (PSG) or an apnea-hypopnea index (AHI) >5 events/hr, ...
The circulating levels of CD4+t helper cells are higher in bipolar disorder as compared to major depressive disorder KU Leuven
INTRODUCTION: Clinical differentiation between bipolar disorder (BD) and major depressive disorder (MDD) is difficult. Research has therefore focused on discriminatory biological markers. Previous studies in MDD reported T cell deficits, while the limited studies in BD reported T cell activation. Studies directly comparing circulating numbers of T cells and T cell subsets between BD and MDD are lacking. The studies in the MOODINFLAME consortium ...
Common and diagnosis-specific fractional anisotropy of white matter in schizophrenia, bipolar disorder, and major depressive disorder : evidence from comparative voxel-based meta-analysis Ghent University Vrije Universiteit Brussel
Functional versus syndromal recovery in patients with major depressive disorder and bipolar disorder Ghent University
Self-management education for patients with bipolar disorder KU Leuven
Introduction and background Bipolar disorder (BD) is a severe chronic mental illness characterised by fluctuating mood and activity patterns, alternating between euthymic, hypo-manic or manic, major depressive, and mixed-mood episodes. The diagnosis can be classified according to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders as a bipolar I disorder when a service user endures at least one manic episode. When ...