Projects
Association of functional variations in brain-expressed miRNA genes with bipolar disorders and schizophrenia University of Antwerp
Analysis of kynurenines in serum of bipolar patients and their association with affective and cognitive symptoms. University of Antwerp
The organization of mental health services for children and adolescents in Belgium Ghent University
The Belgian mental health care sector is trying to reorganise the provision of mental health care services for children and adolescents. In order to support the policy makers this research aims at:
- Gather evidence and knowledge to develop a general framework for organising child and adolescent mental health services. This framework should not develop but create opening towards eventually developing more punctual analyses for the ...
Psych-STRATA - A Stratified Treatment Algorithm in Psychiatry: A program on stratified pharmacogenomics in severe mental illness KU Leuven
A key problem in Mental Health is that up to one third of patients suffering from major mental disorders develop resistance against drug therapy. However, patients showing early signs of treatment resistance (TR) do not receive adequate early intensive pharmacological treatment but instead they undergo a stepwise trial-and-error treatment approach. This situation originates from three major knowledge and translation gaps: i.) we lack ...
Improving treatment strategies for different depressive disorders by discovery of novel drug target candidates and discriminatory diagnostic biomarkers. University of Antwerp
Peroxisomes and vision: what is the role of peroxisomal oxidation in the retina? KU Leuven
The crucial function of peroxisomes for vision is illustrated by the fact that prominent ophthalmological pathology, including retinopathy, occurs in nearly all peroxisomal diseases. Peroxisomes are subcellular organelles that play an essential role in oxygen and lipid metabolism, but their precise contribution to the maintenance of tissue homeostasis is still largely obscure. According to our preliminary data, the retina of mice with ...