Projects
An epigenetic DNA modification signature as a biomarker for prognosis in children with neuroblastoma Ghent University
We wish to validate a DNA methylation prognostic classifier that can differentiate between high-risk and low-risk neuroblastoma patients. To select candidate markers, MBD2-sequencing will be performed on primary tumor samples, combined with an integrative analysis of earlier research results. Using MSP, these markers will then be validated in independent patient sets and on patient bone marrow and serum samples.
The use of Rab27B effector proteins as biomarker or as potential target in estrogen receptor positi Ghent University
Cardiac biomarkers, two-dimensional Speckle Tracking and Tissue Doppler Imaging for objective assessment of mitral and aortic regurgitation in horses Ghent University
Cardiac valvular regurgitation is frequently found in sport horses, especially at the mitral and aortic valves. New tissue Doppler imaging, and biochemical blood examination for cardiac biomarkers will be used to quantify valvular regurgitation and to identify prognostic parameters.
A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN) Ghent University
Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. SOCAN will contribute to the (early) diagnosis and follow up of cancer via a new detection paradigm, i.e. singlet oxygen-based photoelectrochemical detection of cancer biomarkers. Those biomarkers are increasingly discovered and validated, but the detection necessitates rapid, accurate and sensitive devices. To achieve this, the combined use of ...
SensApp: Super-sensitive detection of Alzheimer’s disease biomarkers in plasma by an innovative droplet split-and-stack approach (OZR EU Bonus) Vrije Universiteit Brussel
A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN). University of Antwerp
A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN). University of Antwerp
A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN). University of Antwerp
BIOMARKED Ghent University
BIOMARKED is the Ghent University business unit assisting researchers in translation of pre-clinical translational biomarker research towards opportunities for Pharma/Biotech companies in developing diagnostics and targeted therapies in the field of oncology, HIV and ageing diseases. Specific focus of BIOMARKED is on the most innovative technology platforms for the identification, validation of novel and more accurate biomarkers for risk ...