Projects
Analysis of ethyl glucuronide in hair as biomarker of alcohol intake. University of Antwerp
Plasma cfRNA biomarker tail genes for cancer screening and monitoring Ghent University
Circulating nucleic acids in blood plasma form an attractive resource to study human health and disease. We examined plasma cell-free RNA profiles for a variety of cancer types and demonstrated the potential of using patient-specific alterations in cell-free RNA profiles for discriminating cancer patients from controls. This method could open novel opportunities for cancer screening and therapy response monitoring. While the method has been ...
ADMIRE: Association, causality and biomarker Discovery in translational MIcrobiome REsearch. Hasselt University
Development of BioMArker toolkit for early diagnosis of Gastro-Intestinal dysbiosis in chiCKens (BioMAGICK) Ghent University
The aim of this project is the development of a diagnostic tool for intestinal health in broiler chickens.
Targeting radiotherapy resistance in Head and Neck Cancers: the potential biomarker role of TIPRL1 and CIP2A, two cellular inhibitors of Protein Phosphatase 2A KU Leuven
Being one of the main post-translational modifications, reversible protein phosphorylation is of major importance in signal transduction regulation. Over the years, the kinases phosphorylating many substrates have been extensively studied, while the protein phosphatases have been lagging behind. The PP2A-like phosphatases PP2A, PP4 and PP6, all have been shown to play a role in the regulation of tumorigenesis and the DNA damage response ...
HIV-infection and air pollution as emerging cardiovascular risk factors in the Cape Town region: Are changes in the retinal microvasculature a biomarker of effect? Hasselt University
Muscle functional MRI as an innovative biomarker for fiber type composition. Study in healthy control subjects and chronic low back pain patients. Ghent University
The invasive character of biopsy restricts extensive research on muscle fiber typing in trunk muscles. A noninvasive, in vivo alternative for biopsy may be found in Magnetic Resonance Imaging (MRI). The objective of this project is to validate T2 relaxation time as an innovative biomarker for fiber type distribution and to gain fundamental insight in structural subdivision in lumbar muscles.