Projects
Creating deigner bugs for the production of specialty carbohydrates Ghent University
The overall goal of this project is obtaining the investment requirements of venture capitalists, i.e., a convincing proof-of-concept, a strong IP portfolio, a business and financial plan, etc. enabling the creation of a white biotech spin-off engaged in the development, microbial production and commercialization of specialty carbohydrates for use as a food or pharmaceutical ingredient.
Bioelectrochemical systems as concentration cells for nutrients and organics Ghent University
Biocatalysis can be combined with membrane electrolysis for the production and separation of nutrients such as nitrogen and potassium. In this project we will develop a novel method to harvest organic acids from fermentation besides improving anaerobic digestion.
Construction and optimization of the production pathway of chitosan Ghent University
Pathways to chito oligosaccharides production; Integrating synthetic biology and metabolic engineering for pathway optimization
Metabolic and Enzyme Engineering for the Biotechnological Production of Partially Acetylated Chitosans Ghent University
The ChitoBioEngineering project aims at establishing, through genetic, metabolic and enzyme engineering, biotechnological ways of producing fully defined, partially acetylated chitosans. TodayU+2019s commercially available chitosans are produced chemically from chitin isolated from shrimp shell wastes. They can be well defined concerning their degree of polymerisation and degree of acetylation, but they are invariably characterised by a ...
Biosurfing: New-to-nature biosurfactants by metabolic engineering: production and application Ghent University
This project investigates the biotechnological production of new-to-nature en tailor-made glycolipid biosurfactantia. This project aims to expand the range of useful biological biosurfactants beyond the natural variety, to modify them in order to improve their use and application range, satisfying the need for structural diversity in the market.
Valorization of organic side streams U+2013 Development of 2nd generation technologies for the biobased economy in Flanders. Ghent University
The project is subdivided into three components:
- development of a database of organic side streams and technological expertise available in Flanders;
- development of second generation technologies for the transformation of (waste)oils, fats and side streams rich in lignocellulose into feedstocks for bioenergy, chemistry, paper, the building industry, textile, U+2026
- economic, logistic and sustainability ...
Development of a generic platform for the production of speciality carbohydrates (Type 3) Ghent University
The overall goal of this project is the gathering of data in order to support a recently filed patent application and to further valorize recently obtained scientific results. This patent protects technology which allows the in vivo accumulation of high amounts of activated carbohydrates. These activated carbohydrates are precursors of a wide variety of specialty carbohydrates.
Technology development for more efficient production of membrane proteins in Pichia pastoris Ghent University
Although many drugs already target membrane proteins, these often exhibit low affinity for the target protein, requiring them to be administered in high doses administered; or they are not selective enough, which can lead to severe side effects.
To improve these drugs or identify new molecules, we need to we more than likely perform structure-based drug optimisation. For this, however, we need many more three-dimensional structures of ...
Metabolic engineering for the creation of a platform organism with an increased nucleotide sugar pool Ghent University
The goal of this research is to create a platform organism with an increased intracellular pool of UDP-sugars. The developed technology is based on the principles of metabolic engineering of the model organism Escherichia coli. The created mutants will function as glycosylation platforms for the production of various oligosaccharides and glycoconjugates.