Projects
Autophagy dysregulation in cerebral palsy: a common mechanism. University of Antwerp
The role of autophagy in the prevention of oxidative stress and cardiovascular disease by olive polyphenols. University of Antwerp
Autophagy induction as mechanism of action in cardiovascular disease prevention by olive polyphenols. University of Antwerp
Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma. KU Leuven
Autophagy is a well-conserved intracellular catabolic pathway maintaining cellular homeostasis and is governed by various autophagy-related genes (Atg). Defects in autophagy result in various human pathologies such as cancer. Autophagy has a complex role in cancer, where it functions as a tumor suppressor at the initial stage of tumor initiation but in later stages becomes a cancer cell hijacked mechanism to support further tumor ...
Role of autophagy in the cardiovascular system. University of Antwerp
Role of autophagy in the cardiovascular system. University of Antwerp
The role of autophagy in atherosclerosis and normal vascular function. University of Antwerp
Investigations on selected natural product classes as inhibitors of Advanced Glycation Endproducts (AGEs) and modulators of autophagy University of Antwerp
Role of lymphatic endothelial cell-associated autophagy in melanoma dissemination KU Leuven
Lymphatic vessels are a crucial component of the circulatory system that maintains homeostasis by facilitating tissue fluid and dietary fat absorption and aid in inflammatory and immune responses. Disruptions in their function, driving either excessive lymphatic growth or contraction, have been linked to various diseases, including inflammation, cancer metastasis, and lymphedema. Understanding the mechanisms that regulate lymphatic vessel ...