Neutrophil migration and activation in auto-inflammatory diseases: role of the chemokine network and of posttranslational modification of chemokines KU Leuven
Leukocyte migration is crucial during inflammation. It is regulated by a network of molecules including adhesion molecules, leukocyte attractants such as chemokines and their receptors. Although most leukocyte attractants have been identified, posttranslational modifications affecting their activity are still being discovered. These modifications may increase or decrease the activity of attractants and may even result in the generation of ...