Natural and Artifical Genetic Variation in Microbes KU Leuven
One of the main research topics in biology is the identification of the (combination of) mutations that underlie a specific phenotype or physiological adaptation. Many phenotypes and diseases depend on multiple mutations in multiple genes (loci). In many cases, there is a complex interaction between these mutations - a specific mutation may only play a role when other mutations are also present. Complex genetic interactions are present in all ...