Treatment and prevention of thrombotic thrombocytopenic purpura in a unique animal model. KU Leuven
Thrombotic thrombocytopenic purpura (TTP) is a condition of the Blood characterized by systemic thromboses, hemolysis and thrombocytopenia. The disease is rather rare, but mortal. Current therapy has reduced mortality, but is pragmatic involving delivery of donor plasma products through a catheter. This method has the inherent risk of local inflammation, infection, and rejection. Alternative therapies are being developed, but preclinical data ...