Investigating the biomarker potential and pathological role of neuronal- and bacterial- derived extracellular vesicles in Parkinson’s disease. Ghent University
Accumulating evidence indicates that extracellular vesicles (EVs) represent a highly interesting biomarker source. Indeed, neuronal-derived EVs (nEVs) separated from peripheral sources provide a snapshot of ongoing pathological changes in the brain whereas bacterial EVs (bEVs) have shown to reflect microbial dysbiosis. Interestingly, both neuronal changes and microbial dysbiosis are evident in Parkinson’s disease (PD) patients. Additionally, ...