Study of the interaction between external triggers and the airway barrier in asthma and study of the role of gradual introduction of food allergens for induction and/of maintenance of tolerance in food allergy KU Leuven
In the next 5 years I) I will focus on airway inflammation in (non-allergic) asthma. While the underlying mechanisms of the allergic asthma phenotype are well identified, the pathogenesis of non-allergic asthma phenotypes remains largely unexplored. We hypothesize that triggering of epithelial cells (EC) and subsequent activation of innate lymphoid cells (ILCs) are responsible for the pathophysiology of these non-allergic asthma phenotypes by ...