Studying expression of individual alleles could learn us more about possible molecular causes of diseases such as cancer, yet existing methods are too expensive or yield only incomplete information. In this project we will develop a novel, cheaper and more comprehensive methodology, based on population genetics concepts and statistical modelling, and demonstrate its relevance in a cancer case study.
An in vitro and ex vivo Study on the Expression and Role of Dipeptidyl Peptidase 9 in the Lung. University of Antwerp
Towards a discourse-functional analysis of the expression of epistemic stance in Court in Cordoba Spanish. KU Leuven
Influence of culture conditions on the microRNA expression during preimplantation embryo development Ghent University
The involvement of miRNAs in the regulation of the embryonic gene expression will be investigated. The miRNA expression will be determined at different developmental stages and will be compared between in vivo and in vitro embryos. Next, the miRNA expression will be linked to the expression of their target genes and specific miRNAs will be selected for functional analysis.
Functional validation of miRNA variants related to mature miRNA expression levels. University of Antwerp
Minimizing metabolic burden caused by heterologous expression of synthetic pathways: development of sensors & actuators, implementation of a genetic circuit with beta-carotene production in E. coli as case study Ghent University
The expression of synthetic multi-gene pathways in non-native production hosts often results in metabolic burden, which is detrimental for productivity. A novel genetic circuit will be developed which specifically controls the expression of the heterologous pathway, so that metabolic burden can be avoided. This novel synthetic biology tool will be validated using beta-carotene production in E. coli as case study.
The link between changes in life history traits and gene expression levels under stressful conditions in the waterflea Daphnia magna. KU Leuven
The life and thought of northern prehistoric hunter-gatherers: ethnographical and ethnoarchaeological theory and analysis of the behavioral and material expression of the relationship between ideology and ecology Ghent University
The research proposal consists of the application of the new anthropological paradigm to the study of northern European prehistoric hunter-gatherers with specific focus on the relationship between ecology - the reality of the world in which human beings must survive - and ideology - the human cognition and perception of that world. The new anthropological paradigm sees ecology and ideology as dynamic and dialectic entities, whose relationship ...