Publications
A randomized controlled trial of single-class maintenance therapy with abacavir/lamivudine/zidovudine after standard triple antiretroviral induction therapy: : final 96-week results from the FREE study. Vrije Universiteit Brussel
OBJECTIVES: The aim of the study was to test the antiviral efficacy of a triple nucleoside reverse transcriptase inhibitor (NRTI) regimen, with potential beneficial metabolic effects, as maintenance therapy after induction with dual NRTIs and a boosted protease inhibitor (PI).
METHODS: An open-label, noninferiority study was carried out. Antiretroviral therapy (ART)-naïve patients with CD4 count ≤ 350 cells/μL and HIV-1 RNA >30000 ...
Interruption or deferral of antiretroviral therapy reduces markers of bone turnover compared with continuous therapy: The SMART Body Composition substudy Institute of Tropical Medicine
Retention and predictors of attrition among patients who started antiretroviral therapy in Zimbabwe's national antiretroviral therapy programme between 2012 and 2015 Institute of Tropical Medicine Vrije Universiteit Brussel
BACKGROUND: The last evaluation to assess outcomes for patients receiving antiretroviral therapy (ART) through the Zimbabwe public sector was conducted in 2011, covering the 2007-2010 cohorts. The reported retention at 6, 12, 24 and 36 months were 90.7%, 78.1%, 68.8% and 64.4%, respectively. We report findings of a follow-up evaluation for the 2012-2015 cohorts to assess the implementation and impact of recommendations from this prior ...
Episodic antiretroviral therapy increases HIV transmission risk compared with continuous therapy Institute of Tropical Medicine University of Antwerp
Multi-state models for the analysis of time-to-treatment modification among HIV patients under highly active antiretroviral therapy in Southwest Ethiopia Hasselt University
Predictors of immunological failure of antiretroviral therapy among HIV infected patients in Ethiopia: a matched case-control study Institute of Tropical Medicine
BACKGROUND: In resource constrained settings, immunological assessment through CD4 count is used to assess response to first line Highly Active Antiretroviral Therapy (HAART). In this study, we aim to investigate factors associated with immunological treatment failure.
METHODS: A matched case-control study design was used. Cases were subjects who already experienced immunological treatment failure and controls were those without ...
Persons living with HIV infection on antiretroviral therapy also consulting traditional healers: a study in three African countries Institute of Tropical Medicine University of Antwerp
Traditional healers provide healthcare to a substantial proportion of people living with HIV infection (PLHIV) in high HIV burden countries in sub-Saharan Africa. However, the impact on the health of retained patients visiting traditional healers is unknown. In 2011, a study to asses adherence to anti-retroviral therapy (ART) performed in 18 purposefully selected HIV treatment centers in Tanzania, Zambia and Uganda showed that 'consulting a ...
Retention and viral suppression among patients on antiretroviral therapy before and after the implementation of the HIV "Treat all" guidelines in Zimbabwe Vrije Universiteit Brussel
A qualitative assessment of a community antiretroviral therapy group model in tete, mozambique. Vrije Universiteit Brussel
To improve retention on ART, Médecins Sans Frontières, the Ministry of Health and patients piloted a community-based antiretroviral distribution and adherence monitoring model through Community ART Groups (CAG) in Tete, Mozambique. By December 2012, almost 6000 patients on ART had formed groups of whom 95.7% were retained in care. We conducted a qualitative study to evaluate the relevance, dynamic and impact of the CAG ...