Keratinocyte/dendritic cell interactions in the skin determines allergic sensitization and the severity of asthma to house dust mite allergen Ghent University
Asthma is a chronic inflammatory disease of the airways that is seen increasingly in westernalized countries. Studies have shown that a majority of patients with asthma have suffered from atopic dermatitis (AD) in their childhood. Moreover, patients with AD develop more severe steroid-resistant forms of asthma. The mechanisms involved in the progression from AD to asthma are currently unknown. Several reports argue that this might mainly due ...