A new era of virtual histology: novel contrast agents for 3D multi-tissue imaging using contrast-enhanced computed tomography KU Leuven
Biological tissues have a spatial heterogeneity. Thus, 2D measurements like histomorphometry only partially reveal their full 3D morphology. We propose contrast-enhanced computed tomography (CE-CT) for 3D structural quantification of biological tissues and 3D immunological imaging. Previously, we explored commercially available and in-house synthesized contrast agents (polyoxometalates - POMs). In this project, as pioneers in the field, we ...