Projects
The IncuCyte S3/Organoid platform for live cell culture imaging and kinetic multiparameter analysis of state-of-the-art 3D organoid models and complex tissue mimics KU Leuven
Towards Mimicking the Foetal Liver Niche: Engineering 3D Hydrogel Systems for in-vitro Culture of Hematopoietic Stem Cells KU Leuven
Within my PhD, I will be working on the development of 3D culture systems for the in-vitro culture of hematopoietic stem/progenitor cells (HSPCs), which are a small population of stem cells giving rise to all blood cells during the lifespan of the organism. These 3D culture system will be designed to mimics key biophysical and biological features of the fetal liver (FL) niche, the home place of these stem cells during mammalian development. ...
Screening platform for peripheral neuropathies in induced pluripotent stem cell derived 2D and 3D models. University of Antwerp
Business development of a drug screening Spin-off company based on 2D & 3D human iPSC-derived liver cell models for NASH & (i)DILI. KU Leuven
Bioreactor infrastructure for upscaled culture of organoids and tumoroids. University of Antwerp
Development of next-generation 3D brain organoids for the study and modulation of immunemediated neurodegeneration in cerebrovascular disease. University of Antwerp
In-vitro Paraxial Mesoderm Morphogenesis in 3D Artificial Extracellular Micro Environments KU Leuven
Paraxial mesoderm plays a significant role in somitogenesis, which further gives rise to skeletal muscle, tendon, cartilage and skin. In vitro studies have been mainly performed in 2D culture; however, this system can be overly reductionistic and disregards the complexity of the physiological structures, including multicellular interaction and the interaction between cells and extracellular matrices (ECM) . By utilizing 3D organoid culture ...