Optical genome mapping for comprehensive genetic analysis of sarcomas in a diagnostic setting. KU Leuven
Malignant soft tissue and bone tumors, also called sarcomas, are rare mesenchymal tumors that are characterized by a high heterogeneity in terms of histological presentation, clinical disease course and underlying genetic landscape. The identification of genetic aberrations significantly adds to a correct diagnosis of sarcomas, which is strongly associated with patient treatment and outcome. However, detecting these genetic aberrations in ...