Publications
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A multiple linear regression analysis of factors affecting the simulated Basic Life Support (BLS) performance with Automated External Defibrillator (AED) in Flemish lifeguards KU Leuven
BACKGROUND: Research investigating lifeguards' performance of Basic Life Support (BLS) with Automated External Defibrillator (AED) is limited. AIM: Assessing simulated BLS/AED performance in Flemish lifeguards and identifying factors affecting this performance. METHODS: Six hundred and sixteen (217 female and 399 male) certified Flemish lifeguards (aged 16-71 years) performed BLS with an AED on a Laerdal ResusciAnne manikin simulating an adult ...
Incontinence-associated dermatitis (IAD) : an update Ghent University
Incontinence-associated dermatitis (IAD) is one of the clinical manifestations of moisture-associated skin damage (MASD). IAD is a common problem in patients with faecal and/or urinary incontinence and management is an important challenge for nurses. The aim of this article is to provide a brief update on IAD epidemiology, pathophysiologic IAD observation and classification and management.
Bioelectronics in the brain-gut axis: focus on inflammatory bowel disease (IBD) KU Leuven
Accumulating evidence shows that intestinal homeostasis is mediated by cross-talk between the nervous system, enteric neurons and immune cells, together forming specialized neuroimmune units at distinct anatomical locations within the gut. In this review, we will particularly discuss how the intrinsic and extrinsic neuronal circuitry regulates macrophage function and phenotype in the gut during homeostasis and aberrant inflammation, such as ...
Worries and concerns of Inflammatory Bowel Disease (IBD) patients in Belgium – a validation of the Dutch Rating Form KU Leuven
OBJECTIVES: Worry is the most common psychological complaint among patients with Inflammatory Bowel Disease (IBD). This study aimed to translate and test the psychometric properties the Rating Form of IBD Patient Concerns (RFIPC) among Dutch-speaking patients with IBD in Belgium. It also aimed to describe worries and concerns, and to examine possible differences in worry patterns between patients with different disease types and disease ...
Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD) KU Leuven
Air pollution causes significant morbidity and mortality in patients with inflammatory airway diseases (IAD) such as allergic rhinitis (AR), chronic rhinosinusitis (CRS), asthma, and chronic obstructive pulmonary disease (COPD). Oxidative stress in patients with IAD can induce eosinophilic inflammation in the airways, augment atopic allergic sensitization, and increase susceptibility to infection. We reviewed emerging data depicting the ...
Oncostatin M as a new diagnostic, prognostic and therapeutic target in inflammatory bowel disease (IBD) KU Leuven
Introduction: Given the high rate of primary and acquired resistance to current inflammatory bowel disease (IBD) treatments, novel drug targets and biomarkers that aid in therapeutic prediction are eagerly awaited. Furthermore, postponing treatment initiation because of a diagnostic delay profoundly affects patient well-being and overall disease evolution. Among the emerging targets and biomarkers, oncostatin M (OSM) has gained much interest in ...
Exploratory study on cognitive abilities and social responsiveness in children with 22q11.2 deletion syndrome (22q11DS) and children with idiopathic intellectual disability (IID) KU Leuven
BACKGROUND: Development of cognitive skills and social responsiveness are areas of concern in children with 22q11.2 deletion syndrome (22q11DS). It remains unclear if the cognitive and social profiles and trajectories are syndrome-specific or similar to those of children with idiopathic intellectual disabilities (IID) with or without comorbid autism spectrum disorder (ASD). AIMS AND METHODS: In this exploratory study, we examined and compared ...
Optimization of SeDeM Diagram Expert System: Improved Cohesion Index's (Icd) Methodology. Vrije Universiteit Brussel
In this study, we suggest optimizing the methodology to determine the Cohesion Index (Icd) in order to avoid mistaken characterizations due to powder bulk density. For this purpose, five different excipients, with different bulk densities and of different chemical nature, were compressed at different heights. Their compression and their tablet characterization enable establishing a powder weight for compression in accordance with its bulk ...