Pathophysiological determinants of exercise intolerance in chronic heart failure; focus on endothelial and skeletalmuscle dysfunction. University of Antwerp
The present projects aim to i) investigate and modify pathways, responsible for deficient bone marrow (BM)-related progenitor cells, which are considered key players in the process of endothelial repair; ii) study the effect of ventricular assist support on ED and repair, as well as exercise capacity, in patients with terminal heart failure and to relate these findings to BM suppression (see i); iii) further explore the contribution of skeletal ...