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Mothers' willingness to pay for daughters' HPV vaccine in northern Vietnam Institute of Tropical Medicine

Ha Dinh Thu, Huong Nguyen Thanh, Thuy Hua Thanh, Le Nguyen Hai, Van Tran Thi, Nguyen Manh Tri, Anne Buvé

HPV vaccine is effective in preventing Human papillomavirus, the main cause of cervical cancer. In Vietnam, at first, it was subsidized at $5░a dose and reached the coverage of 96% in 2 pilot provinces, indicating potentially high acceptance. Currently, it is provided at $120-195 for three doses. This is a cross-sectional study, conducted in two northern rural districts of Vietnam. Researchers present findings to show 53.1% of mothers stated ...

Initial suboptimal CD4 reconstitution with antiretroviral therapy despite full viral suppression in a cohort of HIV-infected patients in Senegal Institute of Tropical Medicine

G Batista, Anne Buvé, N F Ngom Gueye, N M Manga, M N Diop, K Ndiaye, A Thiam, F Ly, A Diallo, C T Ndour, et al.

OBJECTIVE: We determined the risk factors and incidence of clinical events associated with suboptimal immune reconstitution (SIR) defined by an increase in CD4 inferior to 50 cells/μL, from inclusion up to six months of antiretroviral treatment (ARVT), in patients with an undetectable viral load (<50 copies/mL).

METHODS: Logistic regression and Cox's proportional hazards model were used to examine risk factors for SIR and the ...

Assessment of HIV-related risky behaviour: a comparative study of face-to-face interviews and polling booth surveys in the general population of Cotonou, Benin Institute of Tropical Medicine

L. Béhanzin, S. Diabate, I. Minani, C.M. Lowndes, M.C. Boily, A.C. Labbé, S. Anagonou, D.M. Zannou, Anne Buvé, M. Alary, et al.
OBJECTIVES: During the 2008 HIV prevalence survey carried out in the general population of Cotonou, Benin, face-to-face interviews (FTFI) were used to assess risky behaviours for HIV and other sexually transmitted infections (STI). We compared sexual behaviours reported in FTFI with those reported in polling booth surveys (PBS) carried out in parallel in an independent random sample of the same population. METHODS: In PBS, respondents grouped by ...

Clinical characteristics associated with Mycoplasma genitalium infection among women at high risk of HIV and other STI in Uganda Institute of Tropical Medicine

JUDITH VANDEPITTE, J Bukenya, P. Hughes, E. Muller, Anne Buvé, R. Hayes, H.A. Weiss, H Grosskurth
BACKGROUND: : Mycoplasma genitalium is a common infection of the genitourinary tract, but its pathogenic effects have not been well described, especially in women. The increasing evidence that M. genitalium is associated with HIV infection calls for an urgent consensus on how best to control this infection. The aim of this study was to describe symptoms and signs associated with M. genitalium infection among high-risk women in Uganda. METHODS: : ...

Prevalence and correlates of Mycoplasma genitalium infection among female sex workers in Kampala, Uganda Institute of Tropical Medicine

J. Vandepitte, E. Muller, J Bukenya, S Nakubulwa, N. Kyakuwa, Anne Buvé, H. Weiss, R. Hayes, H Grosskurth
Background. The importance of Mycoplasma genitalium in human immunodeficiency virus (HIV)-burdened sub-Saharan Africa is relatively unknown. We assessed the prevalence and explored determinants of this emerging sexually transmitted infection (STI) in high-risk women in Uganda.Methods. Endocervical swabs from 1025 female sex workers in Kampala were tested for Mycoplasma genitalium using a commercial Real-TM polymerase chain reaction assay. ...

Double ethical review of North-South collaborative clinical research: hidden paternalism or real partnership? [viewpoint] Institute of Tropical Medicine

Raffaella Ravinetto, Anne Buvé, T Halidou, Pascal Lutumba, A Talisuna, M Juffrie, D'Alessandro, Marleen Boelaert
Despite their universal character, the ethical principles governing clinical research need to be translated into procedures and practices, which will vary among countries and regions because of differences in local cultural norms and in the available resources. Double ethical review, by which a research protocol is submitted for ethical clearance both in the country or countries where the research takes place and in the country of the sponsor or ...

Operational assessment of access to ART in rural Africa: the example of Kisantu in Democratic Republic of the Congo Institute of Tropical Medicine

S Van Rompaey, J Kimfuta, P Kimbondo, C Monn, Anne Buvé
Despite the availability of large funds and considerable efforts to improve access to antiretroviral therapy (ART), coverage of treatment with ART remains low in Democratic Republic of the Congo (DRC). We identified the bottlenecks for adults' access to ART in a semi-rural health zone in DRC, compared ART coverage in the urban and rural area and described the outcomes and yield of different HIV testing settings. An operational model was used to ...