Publications

Non-pulsatile tinnitus is considered to be an auditory phantom percept. The extremely emotional context of disabling tinnitus often leads to a higher level of selective attention directed toward the tinnitus. As such, tinnitus is a continuously distracting auditory event. Auditory attention is associated with the activation of the intraparietal sulcus (IPS), and modulating the IPS with 10 Hz transcranial magnetic stimulation (TMS) creates the ...

Objective Tinnitus can be considered an auditory phantom percept, in which patients hear an internal sound in the absence of any external sound source, mimicking tonal memory. Tinnitus however can be perceived exclusively uni- or bilaterally. Methods The neurophysiological differences were investigated between unilateral and bilateral tinnitus using LORETA source localized resting state EEG recordings. Results The difference between unilateral ...

Tinnitus affects 15% of the population. Of these 12% are severely disabled by it. The role of the autonomic system in tinnitus is hardly being investigated. The aim of this study is to investigate the relationship between tinnitus distress and lateralization of the anterior insula, known to be involved in interoceptive awareness and (para)sympathetic changes. For this, Tinnitus Questionnaire scores are correlated to Heart Rate Variability ...

Validation of the Mini-TQ in a Dutch-speaking population: a rapid assessment for tinnitus-related distress. Objective: Up to 30% of the adult population experiences tinnitus at some point in life. The aim of the present study was to validate the Mini-Tinnitus Questionnaire (TQ) in a Dutch-speaking population for measuring tinnitus-related distress and compare it with the extended version normally used in clinical practice and research. ...

Background Tinnitus is an auditory sensation characterized by the perception of sound or noise in the absence of any external sound source. Based on neurobiological research, it is generally accepted that most forms of tinnitus are attributable to maladaptive plasticity due to damage to auditory system. Changes have been observed in auditory structures such as the inferior colliculus, the thalamus and the auditory cortex as well as in ...

Object Tinnitus is an auditory phantom percept related to tonic and burst hyperactivity of the auditory system. Two parallel pathways supply auditory information to the cerebral cortex: the tonotopically organized lemniscal system, and the nontonotopic extralemniscal system, which fire in tonic and burst mode, respectively. Electrical cortex stimulation is a method capable of modulating activity of the human cortex by delivering stimuli in a ...

Tinnitus is an auditory phantom percept with a tone, hissing, or buzzing sound in the absence of any objective physical sound source. About 6% to 25% of the affected people report interference with their lives as tinnitus causes a considerable amount of distress. However, the underlying neurophysiological mechanism for the development of tinnitus-related distress remains not well understood. Hence we focus on the cortical and subcortical source ...

Background:  Transcranial Magnetic Stimulation (TMS) is a method capable of temporarily suppressing tinnitus by delivering tonic or burst stimuli. Burst TMS has a high interindividual variability and low effect size. Tinnitus type and laterality, tinnitus-related distress, and tinnitus duration might contribute to this large individual variation. Methods:  The effect of burst TMS on the auditory cortex in 100 male individuals is evaluated with ...

INTRODUCTION: Spinal cord stimulation is commonly used for neuropathic pain modulation. The major side effect is the onset of paresthesia. The authors describe a new stimulation design that suppresses pain as well as, or even better than, the currently used stimulation, but without creating paresthesia. METHODS: A spinal cord electrode (Lamitrode) for neuropathic pain was implanted in 12 patients via laminectomy: 4 at the C2 level and 7 at the ...