Publications
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The influence of unmeasured confounding on the MR Steiger approach Ghent University
Disentangling indirect effects through multiple mediators without assuming any causal structure among the mediators Ghent University
When multiple mediators exist on the causal pathway from treatment to outcome, path analysis prevails for disentangling indirect effects along paths linking possibly several mediators. However, separately evaluating each indirect effect along different posited paths demands stringent assumptions, such as correctly specifying the mediators' causal structure, and no unobserved confounding among the mediators. These assumptions may be unfalsifiable ...
Estimation and interpretation of vaccine efficacy in COVID-19 randomized clinical trials Ghent University
Target trial emulation on timing of start of renal replacement therapy in acute kidney injury : lessons learned Ghent University
Nonlinear mediation analysis with high‐dimensional mediators whose causal structure is unknown Ghent University
With multiple possible mediators on the causal pathway from a treatment to an outcome, we consider the problem of decomposing the effects along multiple possible causal path(s) through each distinct mediator. Under a path-specific effects framework, such fine-grained decompositions necessitate stringent assumptions, such as correctly specifying the causal structure among the mediators, and no unobserved confounding among the mediators. In ...