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Perimembranous ventricular septal defect following His bundle lead implantation Ghent University

Jan De Pooter, Simon Calle, Thierry Bové, FREDERIC VAN HEUVERSWYN, Frank Timmermans
His bundle pacing (HBP) offers physiologic pacing by placing the pacing lead directly to the His bundle. We present a case in which a HBP lead, implanted at the fragile membranous septum, resulted in a persistent restrictive perimembranous ventricular septal defect (VSD). This complication of HBP has not been reported before but brings new insights in the discussion regarding the optimal position of a pacing lead in the ventricular septum. The ...

Diagnostic accuracy of R‐wave detection by insertable cardiac monitors Ghent University

Margot De Coster, Anthony Demolder, Veerle De Meyer, Filiep Vandenbulcke, FREDERIC VAN HEUVERSWYN, Jan De Pooter
Background: Insertable cardiac monitors (ICM) allow prolonged rhythm monitoring, but the diagnostic performance can be hampered by false positive arrhythmia alerts related to inadequate R‐wave sensing. This study assesses the prevalence and predictors of inadequate R‐wave sensing (both over‐ and undersensing) among different ICM types. Methods: Patients implanted with an ICM at Ghent University Hospital between January 2017 and August 2018 were ...

In-hospital and 12-month follow-up outcome from the ESC-EORP EHRA Atrial Fibrillation Ablation Long-Term registry : sex differences Ghent University

Mihaela Grecu, Carina Blomström-Lundqvist, Josef Kautzner, Cecile Laroche, Isabelle C Van Gelder, Luc Jordaens, Luigi Tavazzi, Robert Cihak, Jose Manuel Rubio Campal, Zbigniew Kalarus, et al.
Aim The purpose of this study was to compare sex differences of atrial fibrillation (AF) catheter ablation (CA) and to analyse the opportunities for improved outcomes. Methods and results All data were collected from the Atrial Fibrillation Ablation Long-Term registry, a prospective, multinational study conducted by the ESC-EORP European Heart Rhythm Association (EHRA) under the EURObservational Research Programme (ESC-EORP). A total of 104 ...

Case report : synergetic effect of ischaemia and increased vagal tone inducing ventricular fibrillation in a patient with Brugada syndrome Ghent University

Sophie C H Van Malderen, Carl J Schultz, Luc Jordaens
Background Brugada syndrome (BS) is a hereditary channelopathy associated with syncope, malignant ventricular arrhythmia, and sudden cardiac death. Right ventricular ischaemia and BS have similar underlying substrates precipitating ventricular tachycardia or fibrillation (VF). Case summary A 72-year-old woman with BS and a stenosis on the proximal right coronary artery received several subsequent implantable cardioverter-defibrillator shocks due ...

Een alarm voor een pacemakerlead en magnetische resonantie : abnormale impedantie en vreemde elektrogrammen Ghent University

Luc Jordaens, Frédéric Lecouvet, Sébastien Marchandise, Peter Goethals
Cardioactive implantable electronic devices are prone to electromagnetic interaction. Pacing dysfunction can be present, and interfere with programmed values. We present a case report where a non-conditional device, coupled to a 24 year old atrial lead showed delayed changes in impedance, with changes in the electrogram at the atrial level. Changes persisted for more than 6 months, when baseline values were restored.

Transveneuze versus subcutane defibrillator bij patiënten met hypertrofe cardio myopathie : een retrospectieve analyse in twee Belgische ziekenhuizen Ghent University

Peter Goethals, Philippe Purnode, FREDERIC VAN HEUVERSWYN, Luc Jordaens
Hypertrofe cardiomyopathie (HCM) is een erfelijke aandoening met een verhoogd risico op plotse dood (SCD). Er zijn geen gerandomiseerde studies om de implantatie van een implantable cardioverter-defibrillator (ICD) in patiënten met HCM te leiden. Aanbevelingen zijn gebaseerd op observationele, retrospectieve cohort studies.

Combining optimized image processing with dual axis rotational angiography : toward low-dose invasive coronary angiography Ghent University

Dimitri Buytaert, BENNY DRIEGHE, FREDERIC VAN HEUVERSWYN, Jan De Pooter, Peter Gheeraert, Daniël De Wolf, Yves Taeymans, Klaus Bacher
Background Dual axis rotational coronary angiography procedures. Methods and Results Twenty patients were examined using to 2.22 mSv in procedures, where the latter is further reduced to 1.79 mSv when excluding ventriculography. Conclusions During invasive coronary angiography, procedures, using 1 effective dose conversion factor of 0.30 mSvGy(-1)cm(-2) is feasible.

Myocardial disease and ventricular arrhythmia in Marfan syndrome : a prospective study Ghent University Vrije Universiteit Brussel

Laura Muiño Mosquera, Hans De Wilde, Daniel Devos, Danilo Babin, Luc Jordaens, Anthony Demolder, Katya De Groote, Daniël De Wolf, Julie De Backer
Background Aortic root dilatation and-dissection and mitral valve prolapse are established cardiovascular manifestations in Marfan syndrome (MFS). Heart failure and arrhythmic sudden cardiac death have emerged as additional causes of morbidity and mortality. Methods To characterize myocardial dysfunction and arrhythmia in MFS we conducted a prospective longitudinal case-control study including 86 patients with MFS (55.8% women, mean age 36.3 ...

Failure to detect life‐threatening arrhythmias in ICDs using single‐chamber detection criteria Ghent University

Roland Stroobandt, Mattias Duytschaever, Teresa Strisciuglio, FREDERIC VAN HEUVERSWYN, Jan De Pooter, Sébastien Knecht, Yves R Vandekerckhove, Andreas Kucher, Rene H Tavernier
Background: There are anecdotal reports of sudden death despite a functional implantable cardioverter defibrillator (ICD). We sought to describe scenarios leading to fatal or near-fatal outcome due to inappropriately inhibited ICD therapy in devices programmed with single-chamber detection criteria. Methods: Programmed settings, episode lists, and intracardiac electrograms from 24 patients with a life-threatening event (n = 12) or fatal outcome ...