Publications
Novel theory and potential applications of central diastolic pressure decay time constant Ghent University
Effect of interstitial fluid pressure on shear wave elastography : an experimental and computational study Ghent University
Objective. An elevated Interstitial Fluid Pressure (IFP) can lead to strain-induced stiffening of poroelastic biological tissues. As Shear Wave Elastography (SWE) measures functional tissue stiffness based on the propagation speed of acoustically induced shear waves, the Shear Wave Velocity (SWV) can be used as an indirect measurement of the IFP. The underlying biomechanical principle for this stiffening behavior with pressurization is however ...
Hydraulic conductivity of human cancer tissue : a hybrid study Ghent University
Background Elevated tumor tissue interstitial fluid pressure (IFP) is an adverse biomechanical biomarker that predicts poor therapy response and an aggressive phenotype. Advances in functional imaging have opened the prospect of measuring IFP non-invasively. Image-based estimation of the IFP requires knowledge of the tissue hydraulic conductivity (K), a measure for the ease of bulk flow through the interstitium. However, data on the magnitude of ...
Ultrasound shear wave elastography in cardiology Ghent University KU Leuven
Uncertainty quantification of the wall thickness and stiffness in an idealized dissected aorta Ghent University KU Leuven
Personalized treatment informed by computational models has the potential to markedly improve the outcome for patients with a type B aortic dissection. However, existing computational models of dissected walls significantly simplify the characteristic false lumen, tears and/or material behavior. Moreover, the patient-specific wall thickness and stiffness cannot be accurately captured non-invasively in clinical practice, which inevitably leads to ...
Assessment of early diastolic intraventricular pressure difference in children by blood speckle tracking echocardiography Ghent University
Global distributions of age- and sex-related arterial stiffness : systematic review and meta-analysis of 167 studies with 509,743 participants Ghent University
Transmural wave speed gradient may distinguish intrinsic myocardial stiffening from preload-induced changes in operational stiffness in shear wave elastography Ghent University KU Leuven
Background: Shear wave elastography (SWE) is a promising technique to non-invasively assess myocardial stiffness based on the propagation speed of mechanical waves. However, a high wave propagation speed can either be attributed to an elevated intrinsic myocardial stiffness or to a preload-induced increase in operational stiffness. Objective: Our objective was to find a way to discriminate intrinsic myocardial stiffening from stiffening caused ...
Morbidity and survival after laparoscopic versus open pancreatoduodenectomy : propensity score matched comparison Ghent University
PurposeTechnical challenges and a perceived higher risk of complications hinder a wide adoption of minimally invasive pancreatoduodenectomy. We aim to further define the place of minimally invasive pancreatoduodenectomy by comparison with the traditional open approach.MethodsA comparison of the surgical outcomes and survival after laparoscopic (LPD) versus open pancreatoduodenectomy (OPD) was retrospectively performed from a prospectively kept ...