Mitochondrial adaptations in the adjacent and remote myocardium of a chronic myocardial infarction KU Leuven
Scarring and remodelling of the left ventricle (LV) after myocardial infarction (MI) results in ischemic cardiomyopathy with reduced contractile function. Regional differences related to persisting ischemia may exist. We investigated the hypothesis that mitochondrial function and structure is altered in the myocardium adjacent to MI with reduced perfusion (MI adjacent ) and less so in the remote, nonischemic myocardium (MI remote). We used a pig ...