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Lung transplant outcome following donation after euthanasia. KU Leuven

Laurens Ceulemans, Diethard Monbaliu, Paul Schotsmans, Steffen Fieuws, Paul De Leyn, Herbert Decaluwé, Hans Van Veer, Lieven Depypere, Jan Van Slambrouck, Jan Gunst, et al.
BACKGROUND: Organ transplantation is hampered by shortage of suitable organs. In countries with a legal framework, organ donation following euthanasia is an option labeled "donation after cardio-circulatory death category V" (DCD-V). We describe our experience with lung transplantation (LTx) after euthanasia and evaluate post-transplant outcome using a matched comparison to DCD-III (withdrawal from life-sustaining therapy) and donation after ...

Long-term outcome results after endovascular aortoiliac aneurysm repair with the bifurcated EXCLUDER Endoprosthesis. KU Leuven

Inge Fourneau, Geert Maleux
OBJECTIVE: To report the long-term outcome of patients presenting with an aortic, aortoiliac, or isolated common iliac aneurysm treated with the bifurcated EXCLUDER Endoprosthesis. Furthermore, potential differences in late outcome results between the original- and low-permeability endoprosthesis were analyzed. METHODS: A retrospective analysis of prospectively collected data of 182 patients who underwent endovascular aneurysm repair with the ...

Effects of left ventricular mass on computed tomography derived fractional flow reserve in significant obstructive coronary artery disease Vrije Universiteit Brussel

Toshimitsu Tsugu, Kaoru Tanaka, Dries Belsack, Hannes Devos, Yuji Nagatomo, Vincent Michiels, Jean-François Argacha, Bernard Cosyns, Nico Buls, Michel De Maeseneer, et al.

BACKGROUND: In significant obstructive coronary artery disease (SOCAD), a mismatch in assessment of severity of coronary artery stenosis may occur between invasive coronary angiography (ICA) and computed tomography (CT) derived fractional flow reserve (FFRCT). The present study aimed to identify the factors giving an FFRCT > 0.80 and leading to an underestimation of coronary artery severity in SOCAD vessels.

METHODS: A total of 141 ...

Prognostic Implications of Right Ventricular Free Wall Strain in Recipients of Cardiac Resynchronization Therapy Vrije Universiteit Brussel

Jan Stassen, Pieter van der Bijl, Xavier Galloo, Kensuke Hirasawa, Edgard A Prihadi, Nina Ajmone Marsan, Jeroen J Bax

Right ventricular (RV) function is an important prognostic marker in cardiac resynchronization therapy (CRT) recipients. Measuring RV systolic function with echocardiography, however, remains challenging due to the complexity of right heart morphology. Evaluation of RV function with RV free wall strain (FWS) may improve risk stratification in recipients of CRT compared with conventional RV function parameters. In 871 recipients of CRT (mean ...

Prevalence of Acute Pulmonary Embolism at Autopsy in Patients With COVID-19. KU Leuven

Thomas Vanassche, Peter Verhamme, Christophe Vandenbriele
To date, the actual prevalence of acute pulmonary embolism (PE) in patients with SARS-CoV-2 infection remains unknown, as systematic screening for PE is cumbersome. We performed a systematic review and meta-analysis on autoptic data to estimate the prevalence of histopathologic findings of acute PE and its relevance as a cause of death on patients with COVID-19. We searched MEDLINE-PubMed and Scopus to locate all articles published in the ...

Heart Failure and Patient-Reported Outcomes in Adults With Congenital Heart Disease from 15 Countries KU Leuven

Koen Luyckx, Alexander Van De Bruaene, Philip Moons
Background Heart failure (HF) is the leading cause of mortality and associated with significant morbidity in adults with congenital heart disease. We sought to assess the association between HF and patient-report outcomes in adults with congenital heart disease. Methods and Results As part of the APPROACH-IS (Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease-International Study), we collected data on HF ...

Heartmate 3 implantation in small patients: CT-guided chest diameter assessment KU Leuven

Joeri Van Puyvelde, Steven Jacobs, Dirk Vlasselaers, Bart Meyns
In recent years, the Heartmate 3 (HM3) has largely replaced the use of other intracorporeal left ventricular assist devices in the adult field. Because the HM3 is larger than the Heartware Ventricular Assist Device, the general consensus was that for small patients, the Heartware Ventricular Assist Device was the most appropriate implantable device option. Our goal was to describe our experiences with the successful implantation of the HM3 in 2 ...

Subxiphoid Versus Unilateral Video-assisted Thoracoscopic Surgery Thymectomy for Thymomas: A Propensity Score Matching Analysis. KU Leuven

Lieven Depypere
BACKGROUND: The appropriate approach for video-assisted thoracoscopic surgery for early stage thymoma remains unclear. The present study aimed to explore the safety and feasibility of subxiphoid and subcostal arch thoracoscopic thymectomy in comparison with unilateral thoracoscopic thymectomy for treatment of early stage thymoma. METHODS: The outcomes of 237 patients without myasthenia gravis who had undergone thoracoscopic thymectomy for ...